KEGG   COMPOUND: C06965
Entry
C06965                      Compound                               
Name
Disopyramide
Formula
C21H29N3O
Exact mass
339.2311
Mol weight
339.4745
Structure
Remark
Same as: D00303
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01B ANTIARRHYTHMICS, CLASS I AND III
    C01BA Antiarrhythmics, class Ia
     C01BA03 Disopyramide
      D00303  Disopyramide (JP18/USAN/INN) <JP>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Antiarrhythmics
   Vaughn Williams-Class I
    Disopyramide
     D00303  Disopyramide (JP18/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   212  Antiarrhythmic agents
    2129  Others
     D00303  Disopyramide (JP18/USAN/INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01653  Antiarrhythmics
   DG01652  Class I antiarrhythmic agent
    DG01649  Class Ia antiarrhythmic agent
     DG00194  Disopyramide
      D00303  Disopyramide
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    DG00194  Disopyramide
     D00303  Disopyramide
Drug classes [BR:br08332]
 Cardiovascular agent
  DG01653  Antiarrhythmics
   D00303  Disopyramide
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Sodium channels
    SCN1A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
    SCN2A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
    SCN3A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
    SCN4A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
    SCN5A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
    SCN8A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
    SCN9A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
    SCN10A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
    SCN11A
     D00303  Disopyramide (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00303  Disopyramide
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D00303
Other DBs
CAS: 3737-09-5
PubChem: 9179
ChEBI: 4657
NIKKAJI: J3.408H
LinkDB
KCF data

ATOM        25
            1   C8x C    26.6090  -17.5457
            2   C8x C    26.6090  -18.9076
            3   C8x C    27.7884  -19.5885
            4   N5x N    28.9679  -18.9076
            5   C8y C    28.9679  -17.5457
            6   C8x C    27.7884  -16.8647
            7   C8x C    31.3267  -18.9076
            8   C8y C    31.3267  -17.5457
            9   C1d C    30.1473  -16.8647
            10  C8x C    32.5062  -19.5885
            11  C8x C    33.6856  -18.9076
            12  C8x C    33.6856  -17.5457
            13  C8x C    32.5062  -16.8647
            14  C1b C    30.1473  -15.5028
            15  C1b C    31.3288  -14.8207
            16  C5a C    28.1508  -15.7752
            17  N1a N    28.1508  -14.4133
            18  O5a O    26.9950  -16.4548
            19  N1c N    31.3288  -13.3240
            20  C1c C    32.4923  -12.6521
            21  C1c C    30.1334  -12.6337
            22  C1a C    28.9625  -13.3097
            23  C1a C    30.1336  -11.2810
            24  C1a C    33.6474  -13.3190
            25  C1a C    32.4924  -11.2812
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     5   9 1
            10    7  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14    8  13 2
            15    9  14 1
            16   14  15 1
            17    9  16 1
            18   16  17 1
            19   16  18 2
            20   15  19 1
            21   19  20 1
            22   19  21 1
            23   21  22 1
            24   21  23 1
            25   20  24 1
            26   20  25 1

» Japanese version

DBGET integrated database retrieval system