KEGG   COMPOUND: C07044
Entry
C07044                      Compound                               
Name
Hydroxyurea;
Hydroxycarbamide
Formula
CH4N2O2
Exact mass
76.0273
Mol weight
76.0547
Structure
Remark
Same as: D00341
Reaction
R10461 R10466
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00785  Cycloserine biosynthesis, arginine/serine => cycloserine
Enzyme
2.6.99.3        3.5.3.25
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XX Other antineoplastic agents
     L01XX05 Hydroxycarbamide
      D00341  Hydroxyurea (USP) <JP/US>
USP drug classification [BR:br08302]
 Antineoplastics
  Antineoplastics, Other
   Hydroxyurea
    D00341  Hydroxyurea (USP)
 Genetic, Enzyme, or Protein Disorder: Replacement, Modifiers, Treatment
  Hydroxyurea
   D00341  Hydroxyurea (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   422  Antimetabolites
    4229  Others
     D00341  Hydroxyurea (USP); Hydroxycarbamide (JAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Ribonucleoside-diphosphate reductase
    RRM2
     D00341  Hydroxyurea (USP) <JP/US>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00341
Other DBs
CAS: 127-07-1
PubChem: 9256
ChEBI: 44423
PDB-CCD: NHY[PDBj]
NIKKAJI: J2.937H
LinkDB
KCF data

ATOM        5
            1   C5a C    25.2773  -18.3400
            2   N1b N    26.4812  -19.0436
            3   N1a N    24.0675  -19.0436
            4   O5a O    25.2773  -16.9385
            5   O1b O    27.6967  -18.3400
BOND        4
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1

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