KEGG   COMPOUND: C07939
Entry
C07939                      Compound                               
Name
Amantadine hydrochloride
Formula
C10H17N. HCl
Exact mass
187.1128
Mol weight
187.7096
Structure
Remark
Same as: D00777
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04B DOPAMINERGIC AGENTS
    N04BB Adamantane derivatives
     N04BB01 Amantadine
      D00777  Amantadine hydrochloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Antiparkinson Agents
  Antiparkinson Agents, Other
   Amantadine
    D00777  Amantadine hydrochloride (JP18/USP)
 Antivirals
  Anti-influenza Agents
   Amantadine
    D00777  Amantadine hydrochloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   116  Antiparkinsonian agents
    1161  Amantadines
     D00777  Amantadine hydrochloride (JP18/USP)
   117  Psychotropics
    1179  Others
     D00777  Amantadine hydrochloride (JP18/USP)
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D00777  Amantadine hydrochloride (JP18/USP)
Drug groups [BR:br08330]
 Antiviral
  DG03029  Anti-influenza virus agent
   DG02841  Viral uncoating inhibitor
    DG00860  Amantadine
     D00777  Amantadine hydrochloride
 Neuropsychiatric agent
  DG01498  NMDA receptor antagonist
   DG00860  Amantadine
    D00777  Amantadine hydrochloride
  DG01967  Antiparkinson agent
   DG00860  Amantadine
    D00777  Amantadine hydrochloride
 Transporter substrate
  DG02854  SLC22A2 substrate
   DG00860  Amantadine
    D00777  Amantadine hydrochloride
Drug classes [BR:br08332]
 Antiviral
  DG03029  Anti-influenza virus agent
   D00777  Amantadine hydrochloride
 Neuropsychiatric agent
  DG01967  Antiparkinson agent
   D00777  Amantadine hydrochloride
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), NMDA
    GRIN (NMDAR)
     D00777  Amantadine hydrochloride (JP18/USP) <JP/US>
Antimicrobials [BR:br08307]
 Antivirals
  Entry, fusion or uncoating inhibitor
   Influenza virus uncoating inhibitor
    D00777  Amantadine hydrochloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00777  Amantadine hydrochloride
Drug metabolizing enzymes and transporters [br08309.html]
 Drug transporters
  D00777
Other DBs
CAS: 665-66-7
PubChem: 10141
ChEBI: 2619
NIKKAJI: J237.251G
LinkDB
KCF data

ATOM        12
            1   C1z C    24.7039  -16.1170
            2   C1x C    23.6594  -16.7180
            3   C1x C    24.0855  -17.5814
            4   C1x C    25.7481  -16.7180
            5   N1a N    24.7096  -14.9036
            6   C1y C    23.6594  -17.9198
            7   C1y C    24.0855  -18.6957
            8   C1y C    25.7481  -17.9198
            9   C1x C    22.3759  -19.1626
            10  C1x C    24.7039  -18.5266
            11  C1x C    25.2406  -19.7693
            12  X   Cl   28.5598  -17.4299
BOND        13
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     6   9 1
            9     6  10 1
            10    7  11 1
            11    7   9 1
            12    8  10 1
            13    8  11 1

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