KEGG   COMPOUND: C08180
Entry
C08180                      Compound                               
Name
Prednisolone acetate;
Prednisolone 21-acetate;
Pricortin
Formula
C23H30O6
Exact mass
402.2042
Mol weight
402.4807
Structure
Remark
Same as: D00980
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AC Corticosteroids for local oral treatment
     A01AC04 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EA Corticosteroids acting locally
     A07EA01 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA04 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AA Corticosteroids, weak (group I)
     D07AA03 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XA Corticosteroids, weak, other combinations
     D07XA02 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB06 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD02 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA04 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
   S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
    S01CB Corticosteroids/antiinfectives/mydriatics in combination
     S01CB02 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
  S02 OTOLOGICALS
   S02B CORTICOSTEROIDS
    S02BA Corticosteroids
     S02BA03 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03B CORTICOSTEROIDS
    S03BA Corticosteroids
     S03BA02 Prednisolone
      D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
  Prednisolone
   D00980  Prednisolone acetate (JP18/USP/INN)
 Ophthalmic Agents
  Ophthalmic Anti-inflammatories
   Glucocorticoids, Ophthalmic
    Prednisolone
     D00980  Prednisolone acetate (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1315  Ophthalmic cortisones
     D00980  Prednisolone acetate (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for  urogenital organs and anus
  30 Hemorrhoid drugs for external use
   D00980  Prednisolone acetate (JP18/USP/INN)
 Agents for integumentary system
  57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
   D00980  Prednisolone acetate (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Designated second-class OTC drugs
  Inorganic and organic chemicals
   Prednisolone acetate
    D00980  Prednisolone acetate (JP18/USP/INN)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Prednisolone acetate
    D00980  Prednisolone acetate (JP18/USP/INN)
Animal drugs in Japan [BR:br08331]
 95  Agents for external use
  953  Analgesics, anti-itchings, astringents and antiinflammatory agents
   9537  Hormone preparations for external use
    C08180  Prednisolone acetate
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01955  Corticosteroid
   DG02068  Glucocorticoid
    DG00093  Prednisolone
     D00980  Prednisolone acetate
Drug classes [BR:br08332]
 Anti-inflammatory
  DG01955  Corticosteroid
   D00980  Prednisolone acetate
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C1 (GR)
     D00980  Prednisolone acetate (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00980  Prednisolone acetate
Other DBs
CAS: 52-21-1
PubChem: 10380
ChEBI: 8380
NIKKAJI: J4.129G
LinkDB
KCF data

ATOM        29
            1   C2x C    26.6700  -19.4600
            2   C5x C    26.6700  -20.8600
            3   C2x C    27.8600  -21.5600
            4   C2y C    29.1200  -20.8600
            5   C1z C    29.1200  -19.4600
            6   C2x C    27.8600  -18.7600
            7   C1x C    30.3100  -21.5600
            8   C1x C    31.5000  -20.8600
            9   C1y C    31.5000  -19.4600
            10  C1y C    30.3100  -18.7600
            11  C1y C    32.7600  -18.7600
            12  C1z C    32.7600  -17.3600
            13  C1x C    31.5000  -16.6600
            14  C1y C    30.3100  -17.3600
            15  C1x C    35.1400  -18.7600
            16  C1x C    35.1400  -17.3600
            17  C1z C    33.9500  -16.6600
            18  O5x O    25.4800  -21.5600
            19  C1a C    29.1200  -18.0600
            20  O1a O    29.1200  -16.6600
            21  C1a C    32.7600  -15.9600
            22  C5a C    33.9500  -14.9100
            23  O1a O    35.1400  -15.9600
            24  C1b C    35.1400  -14.2100
            25  O5a O    32.7600  -14.2100
            26  O7a O    36.3300  -14.9100
            27  C7a C    37.5200  -14.2100
            28  C1a C    38.7100  -14.9100
            29  O6a O    37.5200  -12.8100
BOND        32
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    2  18 2
            22    5  19 1 #Up
            23   14  20 1 #Up
            24   12  21 1 #Up
            25   17  22 1 #Up
            26   17  23 1 #Down
            27   22  24 1
            28   22  25 2
            29   24  26 1
            30   26  27 1
            31   27  28 1
            32   27  29 2

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