| Entry |
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| Name |
3beta(or 20alpha)-hydroxysteroid dehydrogenase;
progesterone reductase;
dehydrogenase, 3beta,20alpha-hydroxy steroid;
3beta,20alpha-hydroxysteroid oxidoreductase
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase
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| Reaction(IUBMB) |
5alpha-androstan-3beta,17beta-diol + NADP+ = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H+ [RN: R04344]
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| Reaction(KEGG) |
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| Substrate |
5alpha-androstan-3beta,17beta-diol [CPD: C12525];
NADP+ [CPD: C00006]
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| Product |
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| Comment |
Also acts on 20alpha-hydroxysteroids.
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| History |
EC 1.1.1.210 created 1986
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| Reference |
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| Authors |
Sharaf MA, Sweet F. |
|---|
| Title |
Dual activity at an enzyme active site: 3 beta,20 alpha-hydroxysteroid oxidoreductase from fetal blood. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.1.1.210 |
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| LinkDB |
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