Entry |
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Name |
chlordecone reductase;
CDR
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
|
Sysname |
chlordecone-alcohol:NADP+ 2-oxidoreductase
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Reaction(IUBMB) |
chlordecone alcohol + NADP+ = chlordecone + NADPH + H+ [RN: R03716]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Chlordecone is an organochlorine pesticide.
|
History |
EC 1.1.1.225 created 1989
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Orthology |
K00037 | 3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase |
|
Genes |
MCC: | 722483 722490(AKR1C4) |
MCF: | 102116844 102117205(AKR1C4) |
CATY: | 105597444 105597447 |
CANG: | 105521699 105521705 |
CJC: | 100405255 100405615(AKR1C4) |
CIMI: | 108292324(AKR1C4) 108292325 |
» show all
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Reference |
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Authors |
Molowa DT, Shayne AG, Guzelian PS. |
Title |
Purification and characterization of chlordecone reductase from human liver. |
Journal |
J Biol Chem 261:12624-7 (1986) |
Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.225 |
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LinkDB |
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