| Entry |
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| Name |
3beta-hydroxy-5alpha-steroid dehydrogenase
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| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase
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| Reaction(IUBMB) |
3beta-hydroxy-5alpha-pregnane-20-one + NADP+ = 5alpha-pregnan-3,20-dione + NADPH + H+ [RN: R07138]
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| Reaction(KEGG) |
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| Substrate |
3beta-hydroxy-5alpha-pregnane-20-one;
NADP+ [CPD: C00006]
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| Product |
5alpha-pregnan-3,20-dione;
NADPH [CPD: C00005];
H+ [CPD: C00080]
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| History |
EC 1.1.1.278 created 2003
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| Reference |
1 |
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| Authors |
Lindemann, P. and Luckner, M. |
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| Title |
Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata. |
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| Journal |
Phytochemistry 46:507-513 (1997) |
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| Reference |
|
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| Authors |
Warneck HM, Seitz HU. |
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| Title |
3 beta-hydroxysteroid oxidoreductase in suspension cultures of Digitalis lanata EHRH. |
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| Journal |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 1.1.1.278 |
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| LinkDB |
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