 | | ENZYME: 1.13.11.10 | |
| Entry |
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| Name |
7,8-dihydroxykynurenate 8,8a-dioxygenase;
7,8-dihydroxykynurenate oxygenase;
7,8-dihydroxykynurenate 8,8alpha-dioxygenase;
7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)
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| Class |
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
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| Sysname |
7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (ring-opening)
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| Reaction(IUBMB) |
7,8-dihydroxykynurenate + O2 = 5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylate [RN: R03253]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylate [CPD: C05641]
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| Comment |
Requires Fe2+.
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| History |
EC 1.13.11.10 created 1965 as EC 1.13.1.10, transferred 1972 to EC 1.13.11.10
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| Pathway |
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| Reference |
1 |
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| Authors |
Kuno, S., Tashiro, M., Taniuchi, H., Horibata, K., Hayaishi, O., Seno, S., Tokuyama, T. and Sakan, T. |
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| Title |
Enzymatic degradation of kynurenic acid. |
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| Journal |
Fed Proc 20:3 (1961) |
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| Other DBs |
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| LinkDB |
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