Entry
Name
4-aminobenzoate 1-monooxygenase;
4-aminobenzoate hydroxylase;
4-aminobenzoate monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)
Reaction(IUBMB)
4-aminobenzoate + NAD(P)H + 2 H+ + O2 = 4-hydroxyaniline + NAD(P)+ + H2O + CO2 [RN:
R02561 R02562 ]
Reaction(KEGG)
Substrate
Product
Comment
A flavoprotein (FAD). Acts on anthranilate and 4-aminosalicylate but not on salicylate (cf. EC
1.14.13.1 salicylate 1-monooxygenase).
History
EC 1.14.13.27 created 1989
Pathway
ec01120 Microbial metabolism in diverse environments
Reference
Authors
Tsuji H, Ogawa T, Bando N, Sasaoka K.
Title
Purification and properties of 4-aminobenzoate hydroxylase, a new monooxygenase from Agaricus bisporus.
Journal
J Biol Chem 261:13203-9 (1986)
Other DBs
UM-BBD (Biocatalysis/Biodegradation Database): 1.14.13.27
LinkDB
All DBs