Entry
Name
questin monooxygenase;
questin oxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening)
Reaction(IUBMB)
questin + NADPH + H+ + O2 = demethylsulochrin + NADP+ [RN:
R02417 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme cleaves the anthraquinone ring of questin to form a benzophenone. Involved in the biosynthesis of the seco-anthraquinone (+)-geodin.
History
EC 1.14.13.43 created 1992
Reference
Authors
Fujii I, Ebizuka Y, Sankawa U.
Title
A novel anthraquinone ring cleavage enzyme from Aspergillus terreus.
Journal
Other DBs
LinkDB
All DBs