ENZYME: 1.14.13.46
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Entry
EC 1.14.13.46 Enzyme
Name
(-)-menthol monooxygenase;
l-menthol monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
(-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)
Reaction(IUBMB)
(-)-menthol + NADPH + H+ + O2 = p-menthane-3,8-diol + NADP+ + H2O [RN:
R02178
]
Reaction(KEGG)
R02178
Reaction
Substrate
(-)-menthol [CPD:
C00400
];
NADPH [CPD:
C00005
];
H+ [CPD:
C00080
];
O2 [CPD:
C00007
]
Product
p-menthane-3,8-diol [CPD:
C02904
];
NADP+ [CPD:
C00006
];
H2O [CPD:
C00001
]
History
EC 1.14.13.46 created 1992
Reference
1 [PMID:
2906604
]
Authors
Madyastha KM, Srivatsan V.
Title
Studies on the metabolism of l-menthol in rats.
Journal
Drug Metab Dispos 16:765-72 (1988)
Other DBs
ExplorEnz - The Enzyme Database:
1.14.13.46
IUBMB Enzyme Nomenclature:
1.14.13.46
ExPASy - ENZYME nomenclature database:
1.14.13.46
BRENDA, the Enzyme Database:
1.14.13.46
CAS:
117590-75-7
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