KEGG   ENZYME: 1.2.1.13
Entry
EC 1.2.1.13                 Enzyme                                 
Name
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating);
triosephosphate dehydrogenase (NADP+);
dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating);
glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating);
NADP+-glyceraldehyde-3-phosphate dehydrogenase;
NADP+-glyceraldehyde phosphate dehydrogenase;
NADP+-dependent glyceraldehyde phosphate dehydrogenase;
NADP+-triose phosphate dehydrogenase;
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating);
GAPDH
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)
Reaction(IUBMB)
D-glyceraldehyde 3-phosphate + phosphate + NADP+ = 3-phospho-D-glyceroyl phosphate + NADPH + H+ [RN:R01063]
Reaction(KEGG)
R01063
Substrate
D-glyceraldehyde 3-phosphate [CPD:C00118];
phosphate [CPD:C00009];
NADP+ [CPD:C00006]
Product
3-phospho-D-glyceroyl phosphate [CPD:C00236];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.2.1.13 created 1961
Pathway
ec00710  Carbon fixation in photosynthetic organisms
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K05298  glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
Genes
ATH: AT1G12900(GAPA-2) AT1G42970(GAPB) AT3G26650(GAPA)
ALY: 9311398 9326040 9327306
CRB: 17885995 17897550 17898235
CSAT: 104710464 104739945 104755567 104757901 104771836 104777631 104779875
EUS: EUTSA_v10004217mg EUTSA_v10004349mg EUTSA_v10007809mg
BRP: 103833307 103843097 103871970 103875281
BNA: 106346458 106349325 106361259 106367141 106400630 106400839 106405503 106409666 106412548
BOE: 106295615 106305800 106308443 106311773 106319595
RSZ: 108805608 108810222 108812248 108822559 108854059 130504155
THJ: 104805297 104813182 104825726
CPAP: 110813067 110818294
CIT: 102614495 102626680
CIC: CICLE_v10001114mg CICLE_v10015476mg
PVY: 116128630 116146945
MINC: 123195489 123202720 123224567
TCC: 18591736 18601182
GRA: 105769022 105770131 105776635 105783386
GHI: 107897324 107905717 107905755 107914182 107917007 107922459 107934914 107935841
GAB: 108450694 108468831 108480988 108489241
HSYR: 120118653 120147744 120159417 120169541 120185813 120190340 120198658 120209850 120212505
DZI: 111280876 111292190 111300461 111311440
EGR: 104419073 104448945
GMX: 100806482 100815649 732571 732655
GSJ: 114390372 114399964 114408495 114414517
PVU: PHAVU_001G098100g PHAVU_009G006600g
VRA: 106753937 106762331
VAR: 108329548 108341301
VUN: 114162988 114163307
VUM: 124831520 124832874
CCAJ: 109791812 109802348
APRC: 113860768 113865873 113866973
MTR: 11428156 11437530
TPRA: 123889407 123899267
CAM: 101493610 101505130
PSAT: 127087680 127126703
VVO: 131596304 131609872 131660350
LJA: Lj1g3v3385810.2(Lj1g3v3385810.2) Lj1g3v3943580.1(Lj1g3v3943580.1)
ADU: 107460215 107494551
AIP: 107604910 107608243 107609606
AHF: 112697048 112705728 112754934 112764375 112785096 112785966
LANG: 109335833 109344011 109347482 109352140 109358522
PCIN: 129286859 129300698
QSA: O6P43_009786 O6P43_016380 O6P43_018788
FVE: 101296006 101307033
RCN: 112177102 112188936
PPER: 18776538 18784386
PMUM: 103330412 103336651
PAVI: 110764330 110768177
PDUL: 117612470 117627459
MDM: 103409404 103425757 103442070
MSYL: 126610959 126626403 126634129
PXB: 103936989 103952908 103961743 103966613
ZJU: 107419772 107427982
MNT: 21390976 21407558
CSAV: 115701450
CSV: 101202856(GAPDH) 101205112
CMO: 103491694 103493832
BHJ: 120081786 120086996
MCHA: 111007569 111016929
CMAX: 111474421 111480365 111481957 111486674
CMOS: 111435144 111442251 111442776 111446791
CPEP: 111785270 111791267 111792213 111797116
RCU: 8273055 8273642
JCU: 105630249 105635196
HBR: 110639836 110648087 110654413 110669260
MESC: 110607108 110613869 110615648 110626980
POP: 112326437 7457998 7474559 7494712
PEU: 105110306 105132106 105132825 105137219
PALZ: 118041836 118042057 118044122 118061901
JRE: 108997409 109006695 109011490 109022238
CILL: 122311510 122313310 122317351 122317760
CAVE: 132178499 132178784 132190442
QSU: 111995850 112016160 112023637
QLO: 115974679 115976310 115981991
TWL: 119993625 119997268 119999232 120008911
VVI: 100246378 100259814
VRI: 117907541 117931339
SLY: 101249445 101253541 101264004 101266713
SPEN: 107007123 107011213 107017598 107017638
SOT: 102587206 102605252 102606161
SSTN: 125854512 125856815 125862523 125862814
SDUL: 129869982 129874292 129881645 129904335
CANN: 107851146 107866774 107870368 107877699
LBB: 132604190 132613886 132621892
NTA: 107767301 107777241 107780142 107796678 107801158 107820790
NSY: 104229906 104234464 104246338
NTO: 104092088 104119702 104120913
NAU: 109206719 109224788 109232207
INI: 109162850 109181961 109184523
ITR: 115996603 116006964 116032742
SIND: 105156113 105158872
OEU: 111380808 111405940
EGT: 105953652 105960013
SSPL: 121755158 121755759 121759083 121759957 121763941 121767243 121772439 121792902 121809421
SMIL: 130995145 131011003
SHIS: 125205609 125212993 125220045 125222363
APAN: 127247017 127257232 127260377
HAN: 110912668 110920787 110940865
ECAD: 122590218 122596564
LSV: 111886224 111921246
CCAV: 112509283 112522570
DCR: 108203025 108205052 108219447 108227329
CSIN: 114278733 114286729
RVL: 131311878 131330807 131333620
AEW: 130772220 130775988 130786580 130787535 130792188
BVG: 104901009 104907408
SOE: 110790548 110805429
CQI: 110685524 110700727 110711214
ATRI: 130810419 130817321 130828347
MOF: 131144468 131162229
NNU: 104591924 104592682 104606825
MING: 122077567 122077761 122083679
TSS: 122654156 122659946
PSOM: 113271433 113281293 113289632 113298929
OSA: 4331495 4336044
DOSA: Os03t0129300-01(Os03g0129300)
OBR: 102704595 102711250
OGL: 127765529 127770523
BDI: 100829538 100846055
ATS: 109754470 109783816
TDC: 119291849 119303962 119355368 119364491
TAES: 123045658 123053529 123093580 123098850 123105786 123189421
TUA: 125538674
LPER: 127297220 127335113
LRD: 124673959 124701300
SBI: 110431784 110436299
ZMA: 103641723 103642790 109943118 542290 542368
SITA: 101752582 101774537
SVS: 117837837 117863891
PVIR: 120642289 120647441 120681642 120688311
PHAI: 112875455 112899553
PDA: 103704929 103712351
EGU: 105042746 105050991 105060347
MUS: 103970142 103972115 103987962 104000636
ZOF: 121980909 121984799 122041998 122046512
DCT: 110100469 110101371
PEQ: 110033351 110036777 110037744
AOF: 109823666 109836656
MSIN: 131236991 131239228
NCOL: 116247479 116257530 116261011
ATR: 18434583 18445484
SMO: SELMODRAFT_179517 SELMODRAFT_181561 SELMODRAFT_270825 SELMODRAFT_271457
PPP: 112277549 112278729 112284651 112284729 112286028 112288602
CRE: CHLRE_01g010900v5
VCN: VOLCADRAFT_76662
CSL: COCSUDRAFT_38051
CVR: CHLNCDRAFT_49269
APRO: F751_4740
OLU: OSTLU_28757 OSTLU_37993
OTA: OT_ostta01g01560 OT_ostta10g03420
BPG: Bathy01g01370 Bathy11g03690
MIS: MICPUN_104695(GAPB) MICPUN_104876(GAPA)
MPP: MICPUCDRAFT_25339(GAPDH_5) MICPUCDRAFT_49403(GAPDH_3)
CME: CYME_CMJ042C
GSL: Gasu_48130
CCP: CHC_T00009438001
 » show all
Reference
1  [PMID:13804190]
  Authors
BRENNEMAN FN, VOLK WA.
  Title
Glyceraldehyde phosphate dehydrogenase activity with triphosphopyridine nucleotide and with diphosphopyridine nucleotide.
  Journal
J Biol Chem 234:2443-7 (1959)
Reference
2
  Authors
Gibbs, M.
  Title
TPN triosephosphate dehydrogenase from plant tissue.
  Journal
Methods Enzymol 1:411-415 (1955)
Reference
3  [PMID:13271400]
  Authors
ROSENBERG LL, ARNON DI.
  Title
The preparation and properties of a new glyceraldehyde-3-phosphate dehydrogenase from photosynthetic tissues.
  Journal
J Biol Chem 217:361-71 (1955)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.13
IUBMB Enzyme Nomenclature: 1.2.1.13
ExPASy - ENZYME nomenclature database: 1.2.1.13
BRENDA, the Enzyme Database: 1.2.1.13
CAS: 37250-87-6
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