| Entry |
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| Name |
fluoroacetaldehyde dehydrogenase
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| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
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| Sysname |
fluoroacetaldehyde:NAD+ oxidoreductase
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| Reaction(IUBMB) |
fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+ [RN: R07156]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme from Streptomyces cattleya has a high affinity for fluoroacetate and glycolaldehyde but not for acetaldehyde.
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| History |
EC 1.2.1.69 created 2003
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| Reference |
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| Authors |
Murphy CD, Moss SJ, O'Hagan D. |
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| Title |
Isolation of an aldehyde dehydrogenase involved in the oxidation of fluoroacetaldehyde to fluoroacetate in Streptomyces cattleya. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Murphy CD, Schaffrath C, O'Hagan D. |
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| Title |
Fluorinated natural products: the biosynthesis of fluoroacetate and 4-fluorothreonine in Streptomyces cattleya. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.2.1.69 |
| ExPASy - ENZYME nomenclature database: | 1.2.1.69 |
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| LinkDB |
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