KEGG   ENZYME: 1.20.1.1
Entry
EC 1.20.1.1                 Enzyme                                 
Name
phosphonate dehydrogenase;
NAD:phosphite oxidoreductase;
phosphite dehydrogenase
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With NAD+ or NADP+ as acceptor
Sysname
phosphonate:NAD+ oxidoreductase
Reaction(IUBMB)
phosphonate + NAD+ + H2O = phosphate + NADH + H+ [RN:R05746]
Reaction(KEGG)
R05746
Substrate
phosphonate [CPD:C06701];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
phosphate [CPD:C00009];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
NADP+ is a poor substitute for NAD+ in the enzyme from Pseudomonas stutzeri WM88.
History
EC 1.20.1.1 created 2001
Orthology
K18916  phosphonate dehydrogenase
Genes
SEEC: CFSAN002050_01105
ENX: NI40_012445
ENZ: G0034_21710(ptxD)
KPN: KPN_pKPN3p05892
KPH: KPNIH24_26515
KPG: KPNIH32_28465
KPC: KPNIH10_26805
KPJ: N559_5253
KPA: KPNJ1_05518
KPX: PMK1_a00057(ptxD)
KPNE: KU54_00065
KPNU: LI86_26935
KOM: HR38_28610
TOE: QMG90_19690(ptxD)
PAES: SCV20265_1024
PAEU: BN889_06572(ghrB1)
PPJ: RK21_02919
PMOS: O165_024050
PFN: HZ99_13350
PMAN: OU5_P0288(ptxD)
PSK: U771_31795
PHF: NLY38_07980(ptxD)
PSC: A458_08040
PSH: Psest_0431
PBM: CL52_03160
PKG: LW136_13155(ptxD)
HPEG: EAO82_15185
HAES: LO767_17880(ptxD)
PBAU: OS670_15255(ptxD)
MAQ: Maqu_1281 Maqu_3239 Maqu_3990
MHC: MARHY1923(ptxD)
MSR: AU15_17790
MARI: ACP86_13635
MLQ: ASQ50_14210
MALL: PBN92_06775
MSHE: MAALD49_04690 MAALD49_40250
ACW: A0J50_18580
ADV: DJ533_01650
SHP: Sput200_3281
SCHK: GII14_20815
SDEO: D0436_23100
MEJ: Q7A_2703
MPIN: LGT42_006305
TGR: Tgr7_0911
GHL: GM160_03835
HAK: KO116_01540
HAXI: HAALTHF_31260n
NIK: F5I99_12635
RMN: TK49_01775
RME: Rmet_2992(ptxD)
CGD: CR3_2656
CUU: BKK79_37720
BVI: Bcep1808_7212
BMK: DM80_1401(ptxD) DM80_6100(ptxD)
BAEN: L3V59_44180
PUT: PT7_2831
AALN: Q3V95_04040
AAQU: D3M96_16500
AAMM: FE795_02080
ACIP: CBP36_01760
ACIN: CBP34_12135
ACIS: CBP35_17180
ATEM: PQV96_19565
DAC: Daci_2673
CTES: O987_10360
ADK: Alide2_1986
RTA: Rta_30250
HCZ: G9Q37_06075
DIA: Dtpsy_1417
ATER: MW290_01895
HAR: HEAR3214(ptxD)
MMS: mma_3043
HHF: E2K99_12370
OFO: BRW83_0327(ptxD)
OAL: NB647_01290
AON: DEH84_08620
SHD: SUTH_02239
GCA: Galf_2928
BEB: AEM42_00165
NRH: T8J41_20080
RHV: BA939_15910 BA939_16115 BA939_16375 BA939_16580
RROS: D4A92_24580
BIC: LMTR13_34860
BROS: QUH67_22990
RBK: E0H22_04240
MEA: Mex_2p0360 Mex_2p1233(ptxD)
MDI: METDI0356(ptxD)
MAQU: Maq22A_5p70080(ldhA)
MOG: MMB17_14420
FIL: BN1229_v1_0982(ptxD)
FIY: BN1229_v1_0986(ptxD)
MAAD: AZF01_22640
PSIN: CAK95_23670
PPHR: APZ00_01925 APZ00_04570 APZ00_05905 APZ00_17900 APZ00_19400 APZ00_24730
LABT: FIU93_31395(ptxD)
SPSE: SULPSESMR1_03725(ptxD)
RID: RIdsm_05895(ptxD)
PALS: PAF20_17915
SMUC: JL100_031705
TII: DY252_19230
THAR: T8K17_25390
DEU: DBW_3423
DEF: CNY67_04440
DMS: E8L03_15975
EFF: skT53_29730
DKN: NHB83_17725
DHM: CYJ49_005170
BLY: A2T55_11240
BRI: FDF13_08575
BLUT: EW640_10550
BSPO: L1F31_18880
PAUT: Pdca_70280
SYND: KR52_11170
PMF: P9303_11271
PMG: P9301_12531
CYT: cce_2560
TER: Tery_0368
ANA: all8087
NPU: Npun_F3301
NSH: GXM_08599
CALN: NIES2098_31840
 » show all
Reference
1  [PMID:11278981]
  Authors
Costas AM, White AK, Metcalf WW
  Title
Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88.
  Journal
J Biol Chem 276:17429-36 (2001)
DOI:10.1074/jbc.M011764200
  Sequence
[psc:A458_08040]
Reference
2  [PMID:11456941]
  Authors
Vrtis JM, White AK, Metcalf WW, van der Donk WA.
  Title
Phosphite dehydrogenase: an unusual phosphoryl transfer reaction.
  Journal
J Am Chem Soc 123:2672-3 (2001)
DOI:10.1021/ja004301k
Other DBs
ExplorEnz - The Enzyme Database: 1.20.1.1
IUBMB Enzyme Nomenclature: 1.20.1.1
ExPASy - ENZYME nomenclature database: 1.20.1.1
UM-BBD (Biocatalysis/Biodegradation Database): 1.20.1.1
BRENDA, the Enzyme Database: 1.20.1.1
CAS: 9031-35-0
LinkDB

DBGET integrated database retrieval system