KEGG   ENZYME: 1.3.1.66
Entry
EC 1.3.1.66                 Enzyme                                 
Name
cis-dihydroethylcatechol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase
Reaction(IUBMB)
cis-1,2-dihydro-3-ethylcatechol + NAD+ = 3-ethylcatechol + NADH + H+ [RN:R05313]
Reaction(KEGG)
R05313
Substrate
cis-1,2-dihydro-3-ethylcatechol [CPD:C06727];
NAD+ [CPD:C00003]
Product
3-ethylcatechol [CPD:C06728];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the ethylbenzene degradation pathway in bacteria.
History
EC 1.3.1.66 created 2000
Pathway
ec00642  Ethylbenzene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Reference
1  [PMID:4699984]
  Authors
Gibson DT, Gschwendt B, Yeh WK, Kobal VM.
  Title
Initial reactions in the oxidation of ethylbenzene by Pseudomonas putida.
  Journal
Biochemistry 12:1520-8 (1973)
DOI:10.1021/bi00732a008
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.66
IUBMB Enzyme Nomenclature: 1.3.1.66
ExPASy - ENZYME nomenclature database: 1.3.1.66
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.66
BRENDA, the Enzyme Database: 1.3.1.66
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