KEGG ENZYME: 1.4.3.11

ENZYME: 1.4.3.11

Entry

EC 1.4.3.11                 Enzyme

Name

L-glutamate oxidase;
glutamate (acceptor) dehydrogenase;
glutamate oxidase;
glutamic acid oxidase;
glutamic dehydrogenase (acceptor);
L-glutamic acid oxidase

Class

Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor

Sysname

L-glutamate:oxygen oxidoreductase (deaminating)

Reaction(IUBMB)

L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2 [RN:R00250]

Reaction(KEGG)

R00250;
(other) R06124

Substrate

L-glutamate [CPD:C00025];
O2 [CPD:C00007];
H2O [CPD:C00001]

Product

2-oxoglutarate [CPD:C00026];
NH3 [CPD:C00014];
H2O2 [CPD:C00027]

Comment

A flavoprotein (FAD).The enzyme from Azotobacter previously listed under this number, which did not produce H2O2, was a crude cell-free extract that probably contained catalase.

History

EC 1.4.3.11 created 1976, modified 1989

Reference

Authors

Kusakabe, H., Midorikawa, Y., Fujishima, T., Kuninaka, A. and Yoshino, H.

Title

Purification and properties of a new enzyme, L-glutamate oxidase, from Streptomyces sp X-119-6 grown on wheat bran.

Journal

Agric Biol Chem 47:1323-1328 (1983)

Other DBs

ExplorEnz - The Enzyme Database:

1.4.3.11