KEGG   ENZYME: 1.5.99.3
Entry
EC 1.5.99.3                 Enzyme                                 
Name
L-pipecolate dehydrogenase;
L-pipecolate:(acceptor) 1,6-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With unknown physiological acceptors
Sysname
L-pipecolate:acceptor 1,6-oxidoreductase
Reaction(IUBMB)
L-pipecolate + acceptor = (S)-2,3,4,5-tetrahydropyridine-2-carboxylate + reduced acceptor [RN:R02206]
Reaction(KEGG)
R02206 > R02205
Substrate
L-pipecolate [CPD:C00408];
acceptor [CPD:C00028]
Product
(S)-2,3,4,5-tetrahydropyridine-2-carboxylate [CPD:C00450];
reduced acceptor [CPD:C00030]
Comment
The product reacts with water to form (S)-2-amino-6-oxohexanoate.
History
EC 1.5.99.3 created 1972, modified 1986, modified 2011
Pathway
ec00310  Lysine degradation
ec01100  Metabolic pathways
Reference
1  [PMID:6051341]
  Authors
Baginsky ML, Rodwell VW.
  Title
Metabolism of pipecolic acid in a Pseudomonas species. V. Pipecolate oxidase and dehydrogenase.
  Journal
J Bacteriol 94:1034-9 (1967)
DOI:10.1128/JB.94.4.1034-1039.1967
Other DBs
ExplorEnz - The Enzyme Database: 1.5.99.3
IUBMB Enzyme Nomenclature: 1.5.99.3
ExPASy - ENZYME nomenclature database: 1.5.99.3
BRENDA, the Enzyme Database: 1.5.99.3
CAS: 9076-63-5
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