| Entry |
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| Name |
12-hydroxydihydrochelirubine 12-O-methyltransferase
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| Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
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| Sysname |
S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase
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| Reaction(IUBMB) |
S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine = S-adenosyl-L-homocysteine + dihydromacarpine [RN: R04705]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019];
12-hydroxydihydrochelirubine [CPD: C05193]
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| Product |
S-adenosyl-L-homocysteine [CPD: C00021];
dihydromacarpine [CPD: C05316]
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| Comment |
This reaction is part of the pathway for synthesis of benzophenanthridine alkaloid macarpine in plants.
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| History |
EC 2.1.1.120 created 1999
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| Pathway |
| ec00950 | Isoquinoline alkaloid biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
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| Reference |
1 |
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| Authors |
Kammerer, L., De-Eknamkul, W. and Zenk, M.H. |
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| Title |
Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum. |
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| Journal |
Phytochemistry 36:1409-1416 (1994) |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.1.1.120 |
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| LinkDB |
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