Entry |
|
Name |
deoxycytidylate C-methyltransferase;
deoxycytidylate methyltransferase;
dCMP methyltransferase
|
Class |
Transferases;
Transferring one-carbon groups;
Methyltransferases
|
Sysname |
5,10-methylenetetrahydrofolate:dCMP C-methyltransferase
|
Reaction(IUBMB) |
5,10-methylenetetrahydrofolate + dCMP = dihydrofolate + deoxy-5-methylcytidylate [RN: R01670]
|
Reaction(KEGG) |
|
Substrate |
5,10-methylenetetrahydrofolate [CPD: C00143];
dCMP [CPD: C00239]
|
Product |
dihydrofolate [CPD: C00415];
deoxy-5-methylcytidylate [CPD: C03495]
|
Comment |
dCMP is methylated by formaldehyde in the presence of tetrahydrofolate. CMP, dCTP and CTP can act as acceptors, but more slowly.
|
History |
EC 2.1.1.54 created 1978
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Reference |
|
Authors |
Kuo TT, Tu J. |
Title |
Enzymatic synthesis of deoxy-5-methyl-cytidylic acid replacing deoxycytidylic acid in Xanthomonas oryzae phage Xp12DNA. |
Journal |
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Other DBs |
ExplorEnz - The Enzyme Database: | 2.1.1.54 |
ExPASy - ENZYME nomenclature database: | 2.1.1.54 |
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LinkDB |
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