KEGG ENZYME: 2.1.1.96

ENZYME: 2.1.1.96

Entry

EC 2.1.1.96                 Enzyme

Name

thioether S-methyltransferase;
S-adenosyl-L-methionine:thioether S-methyltransferase;
thioether methyltransferase

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase

Reaction(IUBMB)

S-adenosyl-L-methionine + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium [RN:R02572]

Reaction(KEGG)

R02572;
(other) R09370

Substrate

S-adenosyl-L-methionine [CPD:C00019];
dimethyl sulfide [CPD:C00580]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
trimethylsulfonium [CPD:C01008]

Comment

Also acts on dimethyl selenide, dimethyl telluride, diethyl sulfide, 1,4-dithiane and many other thioethers.

History

EC 2.1.1.96 created 1990

Pathway

ec00450

Selenocompound metabolism

Orthology

K00562

methyltransferase

Genes

HSA:	11185(INMT)

PTR:	463912(INMT)

PPS:	100986665(INMT)

GGO:	101143120(INMT)

PON:	100171421(INMT)

NLE:	100603670(INMT)

HMH:	116812596(INMT)

MCC:	694969(INMT)

MCF:	102139220(INMT)

MTHB:

126950079

MNI:	105475814(INMT)

CSAB:

103226272(INMT)

CATY:

105596176(INMT)

PANU:

100998123(INMT)

TGE:	112620035(INMT)

MLEU:

105533692(INMT)

RRO:	104663737(INMT)

RBB:	108532381(INMT)

PTEH:

111522205(INMT)

CJC:	100387750(INMT)

SBQ:	101035075(INMT)

CIMI:

108303319(INMT)

CSYR:

103254460(INMT)

MMUR:

105855099(INMT)

LCAT:

123646987(INMT)

OGA:	100957733(INMT)

MMU:	21743(Inmt)

MCAL:

110296762(Inmt)

MPAH:

110317265(Inmt)

RNO:	368066(Inmt)

MCOC:

116098126(Inmt)

ANU:	117720797(Inmt)

MUN:	110555148(Inmt)

CGE:	100773805(Inmt)

MAUA:

101835859(Inmt)

PROB:

127235715(Inmt)

PLEU:

114689706(Inmt)

MORG:

121439573(Inmt)

MFOT:

126509501

AAMP:

119806657(Inmt)

NGI:	103729450(Inmt)

HGL:	101710622(Inmt) 106008943

CPOC:

100724009

NCAR:

124991696

MMMA:

107146148(Inmt)

OCU:	100008695(INMT) 100338404

OPI:	101526879 101531959

TUP:	102502473(INMT)

ORO:	105758206(INMT)

BTA:	527922(INMT)

BOM:	102270640(INMT)

BIU:	109557473(INMT)

BBUB:

102411712(INMT)

BBIS:

104980483(INMT)

CHX:

102186084

OAS:

101123289

BTAX:

128047032(INMT)

ODA:	120877395(INMT)

CCAD:

122438422(INMT)

MBEZ:

129552077(INMT)

SSC:	100512997(INMT)

CFR:	102503927 102504745

CBAI:

105081898(INMT) 105082129

CDK:	105095849 105106408 116154033

VPC:	102537199(INMT)

BACU:

103019292

BMUS:

118900898(INMT)

LVE:

103070876

OOR:	101284322(INMT)

DLE:	111180005(INMT)

PCAD:

102980842(INMT)

PSIU:

116759859(INMT)

NASI:

112406305(INMT)

ECB:

100055070

EPZ:	103541247(INMT)

EAI:	106830978 106831065(INMT)

MNA:	107544372(INMT)

MJV:	108403655(INMT)

TOD:	119244139 119249740

SARA:

101538793(INMT) 101539242

LAV:	100671921(INMT)

TMU:

101350596

ETF:	101652383(INMT)

DNM:	101412422(INMT)

OAA:	100081148(INMT)

ACS:

100553677

ASAO:

132782581 132782593 132782794

XLA:	108696501 108696502 108697004 108697006 108699501 379432(nnmt.L) 399013(inmt.L)

XTR:	100491548 496676(nnmt) 548447 594924(inmt)

NPR:	108799420 108799728 108799731

RTEM:

120915490 120915491 120915505 120915524 120926873 120926876

BBUF:

120996795 120996849 120999241

BGAR:

122926837 122928942

MUO:	115481614 115481769 115481991

GSH:	117347473 117347493 117347584 117347883

BBEL:

109468493 109478432 109485111

SKO:

100367711

PCHN:

125036405

DSV:

119434542

CSCU:

111615693 111641734

SDM:	118188870 118205359

NAI:	NECAME_02876

PVUL:

126812400

GAE:	121366614 121378382 121378383 121378452 121379017 121379235

HRF:

124145666

HRJ:	124258498 124265701 124265717

MYI:

110462853

PMAX:

117341599

LAK:	106157416 106157421 106157433 106157912 106157913 106157914 106162346 106165307 106170527 106180314 106181959

ADF:

107342266

AMIL:

114946916

PDAM:

113682356

PBW:	D172_003270

» show all

Reference

1 [PMID:3350800]

Authors

Mozier NM, McConnell KP, Hoffman JL.

Title

S-adenosyl-L-methionine:thioether S-methyltransferase, a new enzyme in sulfur and selenium metabolism.

Journal

J Biol Chem 263:4527-31 (1988)

Sequence

[mmu:21743]

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.96

IUBMB Enzyme Nomenclature:

2.1.1.96

ExPASy - ENZYME nomenclature database:

2.1.1.96

BRENDA, the Enzyme Database:

2.1.1.96

CAS:	114797-02-3

LinkDB

DBGET integrated database retrieval system