Entry
Name
putrescine carbamoyltransferase;
PTCase;
putrescine synthase;
putrescine transcarbamylase
Class
Transferases;
Transferring one-carbon groups;
Carboxy- and carbamoyltransferases
BRITE hierarchy
Sysname
carbamoyl-phosphate:putrescine carbamoyltransferase
Reaction(IUBMB)
carbamoyl phosphate + putrescine = phosphate + N-carbamoylputrescine [RN:
R01399 ]
Reaction(KEGG)
Substrate
Product
Comment
The plant enzyme also catalyses the reactions of EC
2.1.3.3 ornithine carbamoyltransferase, EC
2.7.2.2 carbamate kinase and EC
3.5.3.12 agmatine deiminase, thus acting as putrescine synthase, converting agmatine [(4-aminobutyl)guanidine] and ornithine into putrescine and citrulline, respectively.
History
EC 2.1.3.6 created 1976
Orthology
K13252 putrescine carbamoyltransferase
Genes
ENG : O2T12_23430(ptcA) O2T12_23900(ptcA)
LMOC : LMOSLCC5850_0036(argF-1)
LMF : LMOf2365_0045(argF-1)
LMOL : LMOL312_0044(argF-1)
LMW : LMOSLCC2755_0041(argF-1)
LMX : LMOSLCC2372_0036(argF-1)
LMZ : LMOSLCC2482_0041(argF-1)
LMOS : LMOSLCC7179_0042(argF-1)
LMOO : LMOSLCC2378_0045(argF-1)
LMOY : LMOSLCC2479_0036(argF-1)
LMOT : LMOSLCC2540_0042(argF-1)
LMOA : LMOATCC19117_0044(argF-1)
LGZ : NCTC10812_01485(ptcA)
LLX : NCDO2118_1801(ptcA2)
SCP : HMPREF0833_10548(argF)
LKL : DKL58_03360(argF) DKL58_03365
EGV : EGCR1_15285(argF) EGCR1_16265
CLOS : DMR38_14275 DMR38_21370
ETM : CE91St48_10650(ptcA)
MMYI : mycmycITA_00744(pyrB)
MCAP : MCCPF38_00767(ptcA_2)
SERI : SERIO_v1c11430(ptcA)
SPRN : S100390_v1c01270(ptcA)
SPIT : STU14_v1c01270(ptcA)
ELE : Elen_0670 Elen_0676 Elen_2191
EYY : EGYY_08400(ArgF) EGYY_08440(ArgF) EGYY_08490(ArgF) EGYY_17800(ArgF)
EGD : GS424_004675 GS424_009280 GS424_013635 GS424_013660 GS424_013725 GS424_016205
AHAT : ADCFC_15810(ptcA_1) ADCFC_19250(ptcA_2) ADCFC_21490(ptcA_3)
» show all
Taxonomy
Reference
Authors
Roon RJ, Barker HA
Title
Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase.
Journal
Sequence
Reference
Authors
Srivenugopal KS, Adiga PR.
Title
Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and properties of a multifunctional enzyme (putrescine synthase).
Journal
J Biol Chem 256:9532-41 (1981)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.3.6
ExPASy - ENZYME nomenclature database: 2.1.3.6
BRENDA, the Enzyme Database: 2.1.3.6
LinkDB
All DBs