benzoyl-CoA [CPD:C00512];
10-deacetyl-2-debenzoylbaccatin III [CPD:C11899]
Product
CoA [CPD:C00010];
10-deacetylbaccatin III [CPD:C11700]
Comment
The enzyme was studied using the semisynthetic substrate 2-debenzoyl-7,13-diacetylbaccatin III. It will not acylate the hydroxy group at 1beta, 7beta, 10beta or 13alpha of 10-deacetyl baccatin III, or at 2alpha or 5alpha of taxa-4(20),11-diene-2alpha,5alpha-diol.
Taxol biosynthesis: molecular cloning of a benzoyl-CoA:taxane 2alpha-O-benzoyltransferase cDNA from taxus and functional expression in Escherichia coli.