KEGG   ENZYME: 2.4.1.54
Entry
EC 2.4.1.54                 Enzyme                                 
Name
undecaprenyl-phosphate mannosyltransferase;
guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase;
GDP mannose-undecaprenyl phosphate mannosyltransferase;
GDP-D-mannose:lipid phosphate transmannosylase;
GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
GDP-alpha-D-mannose:undecaprenyl-phosphate D-mannosyltransferase
Reaction(IUBMB)
GDP-alpha-D-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol [RN:R07257]
Reaction(KEGG)
R07257
Substrate
GDP-alpha-D-mannose [CPD:C00096];
undecaprenyl phosphate [CPD:C17556]
Product
GDP [CPD:C00035];
D-mannosyl-1-phosphoundecaprenol [CPD:C15542]
Comment
Requires phosphatidylglycerol.
History
EC 2.4.1.54 created 1972
Reference
1  [PMID:5350943]
  Authors
Lahav M, Chiu TH, Lennarz WJ.
  Title
Studies on the biosynthesis of mannan in Micrococcus lysodeikticus. II. The enzymatic synthesis of mannosyl-l-phosphoryl-undecaprenol.
  Journal
J Biol Chem 244:5890-8 (1969)
Reference
2  [PMID:17072001]
  Authors
Rush JS, Waechter CJ
  Title
Partial purification of mannosylphosphorylundecaprenol synthase from Micrococcus  luteus: a useful enzyme for the biosynthesis of a variety of mannosylphosphorylpolyisoprenol products.
  Journal
Methods Mol Biol 347:13-30 (2006)
DOI:10.1385/1-59745-167-3:13
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.54
IUBMB Enzyme Nomenclature: 2.4.1.54
ExPASy - ENZYME nomenclature database: 2.4.1.54
BRENDA, the Enzyme Database: 2.4.1.54
CAS: 37277-62-6
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