KEGG   ENZYME: 2.5.1.50
Entry
EC 2.5.1.50                 Enzyme                                 
Name
zeatin 9-aminocarboxyethyltransferase;
beta-(9-cytokinin)-alanine synthase;
beta-(9-cytokinin)alanine synthase;
O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine);
lupinate synthetase;
lupinic acid synthase;
lupinic acid synthetase;
3-O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase
Reaction(IUBMB)
O-acetyl-L-serine + zeatin = lupinate + acetate [RN:R03133]
Reaction(KEGG)
R03133
Substrate
O-acetyl-L-serine [CPD:C00979];
zeatin [CPD:C00371]
Product
lupinate [CPD:C01513];
acetate [CPD:C00033]
Comment
The enzyme acts not only on zeatin but also on other N6-substituted adenines. The reaction destroys their cytokinin activity and forms the corresponding 3-(adenin-9-yl)-L-alanine.
History
EC 2.5.1.50 created 1984 as EC 4.2.99.13, transferred 2002 to EC 2.5.1.50
Pathway
ec00908  Zeatin biosynthesis
ec01110  Biosynthesis of secondary metabolites
Reference
1
  Authors
Entsch, B., Parker, C.W. and Letham, D.S.
  Title
An enzyme from lupin seeds forming alanine derivatives of cytokinins.
  Journal
Phytochemistry 22:375-381 (1983)
Reference
2
  Authors
Mok, D.W.S. and Mok, M.C.
  Title
Cytokinin metabolism and action.
  Journal
Ann Rev Plant Physiol Plant Mol Biol 52:89-118 (2001)
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.50
IUBMB Enzyme Nomenclature: 2.5.1.50
ExPASy - ENZYME nomenclature database: 2.5.1.50
BRENDA, the Enzyme Database: 2.5.1.50
CAS: 88086-35-5
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