Entry
Name
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
BRITE hierarchy
Sysname
ATP:macrolide 2'-O-phosphotransferase
Reaction(IUBMB)
ATP + oleandomycin = ADP + oleandomycin 2'-O-phosphate [RN:
R03780 ]
Reaction(KEGG)
Substrate
Product
Comment
Erythromycin, spiramycin and some other macrolide antibiotics can also act as acceptors.
History
EC 2.7.1.136 created 1992
Reference
Authors
O'Hara K, Kanda T, Kono M.
Title
Structure of a phosphorylated derivative of oleandomycin, obtained by reaction of oleandomycin with an extract of an erythromycin-resistant strain of Escherichia coli.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 2.7.1.136
LinkDB
All DBs