| Entry |
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| Name |
NADH kinase;
reduced nicotinamide adenine dinucleotide kinase (phosphorylating);
DPNH kinase;
reduced diphosphopyridine nucleotide kinase;
NADH kinase
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
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| Sysname |
ATP:NADH 2'-phosphotransferase
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| Reaction(IUBMB) |
ATP + NADH = ADP + NADPH [RN: R00105]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
CTP, ITP, UTP and GTP can also act as phosphate donors (in decreasing order of activity). The enzyme is specific for NADH. Activated by acetate.
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| History |
EC 2.7.1.86 created 1976 (EC 2.7.1.96 created 1978, incorporated 1978)
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| Orthology |
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| Genes |
| NCS: | NCAS_0H01000(NCAS0H01000) |
| NDI: | NDAI_0F02290(NDAI0F02290) |
| TPF: | TPHA_0J02240(TPHA0J02240) |
| TBL: | TBLA_0B05170(TBLA0B05170) |
| TDL: | TDEL_0G01590(TDEL0G01590) |
| KAF: | KAFR_0B06770(KAFR0B06770) |
| KNG: | KNAG_0M00410(KNAG0M00410) |
| CAL: | CAALFM_C307010WA(POS5) |
| NTE: | NEUTE1DRAFT128131(NEUTE1DRAFT_128131) |
| BFU: | BCIN_10g02880(Bcpos5) |
| CCAC: | CcaHIS019_0504090(POS5) |
| ABP: | AGABI1DRAFT99179(AGABI1DRAFT_99179) |
| ABV: | AGABI2DRAFT178464(AGABI2DRAFT_178464) |
| SCM: | SCHCO_02631517(SCHCODRAFT_02631517) |
| PGR: | PGTG_16175 PGTG_18830 |
| PTRC: | PtA15_4A524 PtA15_6A737 |
| PTM: | GSPATT00006279001 GSPATT00009606001 |
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| Reference |
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| Authors |
Griffiths MM, Bernofsky C. |
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| Title |
Purification and properties of reduced diphosphopyridine nucleotide kinase from yeast mitochondria. |
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| Journal |
J Biol Chem 247:1473-8 (1972) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.1.86 |
| ExPASy - ENZYME nomenclature database: | 2.7.1.86 |
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| LinkDB |
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