KEGG   ENZYME: 2.7.1.88
Entry
EC 2.7.1.88                 Enzyme                                 
Name
dihydrostreptomycin-6-phosphate 3'alpha-kinase;
dihydrostreptomycin 6-phosphate kinase (phosphorylating);
ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase
Reaction(IUBMB)
ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate [RN:R03395]
Reaction(KEGG)
R03395
Substrate
ATP [CPD:C00002];
dihydrostreptomycin 6-phosphate [CPD:C01221]
Product
ADP [CPD:C00008];
dihydrostreptomycin 3'alpha,6-bisphosphate [CPD:C01280]
Comment
3'-Deoxydihydrostreptomycin 6-phosphate can also act as acceptor.
History
EC 2.7.1.88 created 1976
Reference
1  [PMID:4121456]
  Authors
Walker JB, Skorvaga M.
  Title
Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives.
  Journal
J Biol Chem 248:2435-40 (1973)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.88
IUBMB Enzyme Nomenclature: 2.7.1.88
ExPASy - ENZYME nomenclature database: 2.7.1.88
BRENDA, the Enzyme Database: 2.7.1.88
CAS: 39391-14-5
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