KEGG   ENZYME: 2.7.7.44
Entry
EC 2.7.7.44                 Enzyme                                 
Name
glucuronate-1-phosphate uridylyltransferase;
UDP-glucuronate pyrophosphorylase;
UDP-D-glucuronic acid pyrophosphorylase;
UDP-glucuronic acid pyrophosphorylase;
uridine diphosphoglucuronic pyrophosphorylase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
Sysname
UTP:1-phospho-alpha-D-glucuronate uridylyltransferase
Reaction(IUBMB)
UTP + 1-phospho-alpha-D-glucuronate = diphosphate + UDP-alpha-D-glucuronate [RN:R01381]
Reaction(KEGG)
R01381
Substrate
UTP [CPD:C00075];
1-phospho-alpha-D-glucuronate [CPD:C05385]
Product
diphosphate [CPD:C00013];
UDP-alpha-D-glucuronate [CPD:C00167]
Comment
Also acts slowly with CTP.
History
EC 2.7.7.44 created 1976
Pathway
ec00040  Pentose and glucuronate interconversions
ec00053  Ascorbate and aldarate metabolism
ec00520  Amino sugar and nucleotide sugar metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:5570433]
  Authors
Roberts RM.
  Title
The formation of uridine diphosphate-glucuronic acid in plants. Uridine diphosphate-glucuronic acid pyrophosphorylase from barley seedlings.
  Journal
J Biol Chem 246:4995-5002 (1971)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.7.44
IUBMB Enzyme Nomenclature: 2.7.7.44
ExPASy - ENZYME nomenclature database: 2.7.7.44
BRENDA, the Enzyme Database: 2.7.7.44
CAS: 52228-05-4
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