| Entry |
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| Name |
glycyrrhizin hydrolase;
glycyrrhizinate beta-glucuronidase;
glycyrrhizin beta-hydrolase;
glycyrrhizinic acid hydrolase
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| Class |
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
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| Sysname |
glycyrrhizinate glucuronosylhydrolase
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| Reaction(IUBMB) |
glycyrrhizin + H2O = beta-D-glucuronosyl-(1->2)-D-glucuronate + glycyrrhetinate [RN: R03906]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
beta-D-glucuronosyl-(1->2)-D-glucuronate;
glycyrrhetinate [CPD: C02283]
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| Comment |
The enzyme from Aspergillus niger is specific for the hydrolysis of the triterpenoid glycoside glycyrrhizin from roots of Glycyrrhiza sp.
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| History |
EC 3.2.1.128 created 1989
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| Reference |
1 |
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| Authors |
Muro, T., Kuramoto, T., Imoto, K. and Okada, S. |
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| Title |
Purification and some properties of glycyrrhizinic acid hydrolase from Aspergillus niger GRM3. |
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| Journal |
Agric Biol Chem 50:687-692 (1986) |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 3.2.1.128 |
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| LinkDB |
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