| Entry |
|
|---|
| Name |
hydroxymandelonitrile lyase;
hydroxynitrile lyase;
oxynitrilase;
Sorghum hydroxynitrile lyase;
(S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase
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|---|
| Class |
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
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| Sysname |
(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)
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| Reaction(IUBMB) |
(S)-4-hydroxymandelonitrile = cyanide + 4-hydroxybenzaldehyde [RN: R02676]
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| Reaction(KEGG) |
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| Substrate |
(S)-4-hydroxymandelonitrile [CPD: C03742]
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| Product |
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| Comment |
Does not accept aliphatic hydroxynitriles, unlike EC 4.1.2.10 (mandelonitrile lyase), EC 4.1.2.46 [aliphatic (R)-hydroxynitrile lyase] and EC 4.1.2.47 [(S)-hydroxynitrile ketone-lyase (cyanide forming)].
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| History |
EC 4.1.2.11 created 1965, modified 1999
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| Pathway |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
| K08249 | hydroxymandelonitrile lyase |
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| Genes |
| SBI: | 110435085 110435343 8066733 |
| PHAI: | 112902845 112903789 |
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| Reference |
1 |
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| Authors |
Bove, C. and Conn, E.E. |
|---|
| Title |
Metabolism of aromatic compounds in higher plants. II. Purification and properties of the oxynitrilase of Sorghum vulgare. |
|---|
| Journal |
J Biol Chem 236:207-210 (1961) |
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| Reference |
|
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| Authors |
Seely MK, Criddle RS, Conn EE. |
|---|
| Title |
The metabolism of aromatic compounds in higher plants. 8. On the requirement of hydroxynitrile lyase for flavin. |
|---|
| Journal |
J Biol Chem 241:4457-62 (1966) |
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.1.2.11 |
| ExPASy - ENZYME nomenclature database: | 4.1.2.11 |
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| LinkDB |
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