Entry
Name
aldehyde oxygenase (deformylating);
decarbonylase;
aldehyde decarbonylase;
octadecanal decarbonylase;
octadecanal alkane-lyase
Class
Lyases;
Carbon-carbon lyases;
Other carbon-carbon lyases
BRITE hierarchy
Sysname
a long-chain aldehyde alkane-lyase
Reaction(IUBMB)
a long-chain aldehyde + O2 + 2 NADPH + 2 H+ = an alkane + formate + H2O + 2 NADP+ [RN:
R03728 ]
Reaction(KEGG)
Substrate
Product
Comment
Contains a diiron center. Involved in the biosynthesis of alkanes. The enzyme from the cyanobacterium Nostoc punctiforme PCC 73102 is only active in vitro in the presence of ferredoxin, ferredoxin reductase and NADPH, and produces mostly C15 and C17 alkanes [2,3]. The enzyme from pea (Pisum sativum) produces alkanes of chain length C18 to C32 and is inhibited by metal-chelating agents [1]. The substrate for this enzyme is formed by EC
1.2.1.80 , acyl-[acyl-carrier protein] reductase.
History
EC 4.1.99.5 created 1989, modified 2011, modified 2013
Pathway
ec00073 Cutin, suberine and wax biosynthesis
ec01110 Biosynthesis of secondary metabolites
Orthology
K14331 fatty aldehyde decarbonylase
Genes
ATH : AT1G02190 AT1G02205(CER1) AT2G37700
ALY : 9315772 9328081 9330760
CRB : 17890234 17899648 17900261 17900889
CSAT : 104700905 104758142 104759026 104770317 104773539 104773540 104773742 104773743 104773763 104773764 104782202 104785716 104787457 104788709 104792563 109124978
EUS : EUTSA_v10007056mg EUTSA_v10009534mg EUTSA_v10016375mg
BRP : 103843834 103857727 103865622 103865625 103867170
BNA : 106392348 106402987 106404754 106407983 106410643 106426031 106427726 106437024 106451050
BOE : 106308419 106329420 106329421 106337750 106339989 106342430
RSZ : 108810757 108837140 108844545 108856796
THJ : 104799403 104810724 104813547
CPAP : 110807870 110816250
CIT : 102609996 102610181 102610308
CIC : CICLE_v10011291mg CICLE_v10019265mg CICLE_v10019279mg
TCC : 108660922 108663945 108663946 18585715 18590332 18607120 18607121 18607128
GRA : 105773703 105774362 105779994 105779995 105792677
GHI : 107900564 107948639 107960346 107961728 107962103 107962105 107962106 121218563
GAB : 108457980 108470923 108484138 108485455 108485729
HSYR : 120119464 120129541 120145735 120146992
DZI : 111282051 111282066 111282088 111293740 111302090 111303798 111309702
EGR : 104430947 104441318 104441320 104441328 104442848 104442849
GMX : 100790115 100805835 100818557
GSJ : 114406437 114406438 114406439 114418764 114418835
PVU : PHAVU_010G040500g PHAVU_010G040600g
VRA : 106772969 106772995 106773669
VAR : 108347155 108347177 108347190
VUN : 114166431 114166486 114167540
CCAJ : 109790836 109792954 109814131 109817909 109817915
APRC : 113850617 113863345
MTR : 11414040 11414816 11430404 11443990 11444136 25500162
TPRA : 123883310 123883311 123885084 123885634 123888818 123888819 123919434 123922160
CAM : 101508006 101514081 101514846
PSAT : 127076644 127076646 127126419 127126421 127126728
VVO : 131601846 131612385 131612386 131616144 131616145 131622919 131622940
LJA : Lj1g3v4156050.1(Lj1g3v4156050.1) Lj3g3v0618210.1(Lj3g3v0618210.1) Lj3g3v0618250.1(Lj3g3v0618250.1) Lj4g3v1120540.1(Lj4g3v1120540.1)
ADU : 107472613 107472630 107494920
AIP : 107605303 107610850 107618742
AHF : 112697362 112701648 112730784 112730831 112769914 112776197 112779428
LANG : 109352187 109361171 109363612
PCIN : 129287775 129288800
FVE : 101297683 101308477 101311999 101312286
RCN : 112181465 112182338 112186659 112187442 112188030 112193250 112195581
PPER : 18785414 18786441 18787082 18787499 18787644
PMUM : 103331413 103331414 103331441 103331464 103344052
PAVI : 110757365 110771793 110771794
PDUL : 117617785 117617786
MDM : 103406883 103428452 103433190
MSYL : 126605177 126613805 126628576 126628577
PXB : 103929751 103929753 103929757 103932050 103965505 103965506
ZJU : 107403676 107403679 107403682 107421712 107421713 125423018
CSAV : 115713279 115713286
CSV : 101203441 101203691 101221193 101222843
CMO : 103483417 103483418 103483426 103498990
BHJ : 120067038 120068459 120072793
MCHA : 111016028 111016029 111016030 111022778
CMAX : 111473822 111473823 111479677 111494235
CMOS : 111431767 111443967 111443973 111464399
CPEP : 111778304 111785111 111789761 111799545 111799672
HBR : 110638963 110641046 110649196
MESC : 110614572 110614939 110614983 110615004 110616986
POP : 18105329 18105332 7463394
PALZ : 118040415 118045229
JRE : 108989715 109008029 109008030
CILL : 122291387 122292858 122293319 122293427
CAVE : 132172701 132177650 132177657 132179844 132181187 132187646 132188697
QSU : 111998302 111998303 111998304 111999683 112009915 112018104 112030629
QLO : 115968885 115968966 115986553 115987043 115987049
TWL : 119982248 119982311 119982317 119983062
VVI : 100243849 100250668 100252221 100256874 100261967 100854413
VRI : 117909465 117931548 117931596 117931863 117931870 117931966 117932772
SLY : 101252060 101263099 101267647 101267934 101268663
SPEN : 107005221 107005457 107008221 107008222 107014415 107014566 107025013
SOT : 102579007 102579333 102579884 102593084 102595750 102599091 102599945
SSTN : 125841317 125865565 125866579 125873065 125875020 125875057
SDUL : 129877629 129884822 129886814 129886815 129889059 129891088 129891099
CANN : 107844046 107844196 107844359 107851087 107851578 107854358 107868261
LBB : 132603730 132611441 132611442 132635292 132645864 132645865
NTA : 107759567 107773304 107774629 107778616 107785373 107800178 107801545 107809310 107817101 107821267 107823602
NSY : 104212478 104227074 104228614 104235229 104240300 104244089
NTO : 104084728 104084731 104096116 104106154 104107044 104116100
NAU : 109209082 109209347 109214395 109222351 109223843 109234408 109234411 109244845
INI : 109182241 109182254 109182262
ITR : 116014996 116015011 116017410 116027583
SIND : 105167221 105167251 105173435 105173436
OEU : 111373242 111373243 111376458 111377333 111410890 111411605
EGT : 105952439 105954794 105954795
SSPL : 121752170 121773259 121774062 121775596 121775769 121777449 121792609 121802233 121804405 121807145
SMIL : 131015843 131022146 131022147 131022151
SHIS : 125196627 125196666 125201589 125202414 125210349 125212942 125218609 125224199
APAN : 127260552 127260768 127262608 127262620 127262638 127264298 127264370
HAN : 110897451 110897561 110912685 110920509
ECAD : 122590796 122595065
CCAV : 112522670 112526942
DCR : 108193604 108193835 108200521 108202980 108216902
CSIN : 114261760 114261768 114301969
RVL : 131333603 131333604 131333605 131333609
CQI : 110688922 110720448 110720450 110720452 110721591 110721593 110721594 110739445
ATRI : 130809722 130827164
MOF : 131165991 131166032 131166546 131166547 131166548
NNU : 104590840 104596252 104596253 104596254 104611270 104611276
MING : 122077770 122079509 122079802 122079803
TSS : 122654307 122658652 122658661 122658674 122658681
PSOM : 113275162 113280221 113285408 113290441 113296001 113304842 113326033 113326085 113336172 113339276 113340194 113349541 113350373 113350987 113352694 113357337
OSA : 4330012 4331117 4336381
DOSA : Os02t0621300-01(Os02g0621300) Os02t0814200-01(Os02g0814200) Os10t0471100-01(Os10g0471100)
OBR : 102703957 102714431 102717322 102718869
OGL : 127753022 127761011 127763336 127769994
BDI : 100825208 100833295 100833807 100833914 100837949
ATS : 109733084 109747194 109756465 109759643 109759677 109765469 109765470 109774093
TDC : 119268601 119268609 119317146 119318483 119320989 119321025 119321193 119324367 119331085 119355884 119355886 119365025
TAES : 100125734 100192181 123045141 123045147 123046137 123054020 123083993 123120828 123120849 123127749 123128943 123139672 123146104 123152997 123169144 123181004 123181005 123186892 123189906 123189907
TUA : 125506190 125506201 125506210 125506221 125515358 125519926 125530343 125530897 125530900
LPER : 127300025 127305393 127307074 127335568
LRD : 124674286 124677032 124687671 124690929 124691050 124705500 124705505
SBI : 8064469 8067437 8072487 8084204 8084699
ZMA : 100273712 100280261 100382841
SITA : 101762753 101769789 101772770 101775794
SVS : 117841046 117848300 117863027 117863265
PVIR : 120646073 120650814 120656480 120682920 120690773 120709010
PHAI : 112874964 112875267 112882648 112899988
PDA : 103699030 103711898 113463032
EGU : 105044200 105044255 105055747
ZOF : 121992367 121996329 122002694 122002705 122009953 122037920
AOF : 109824901 109825477 109832741 109836409 109845087 109849475 109851020
MSIN : 131227730 131227786 131227813 131227832 131227913 131240521 131245798
NCOL : 116266056 116266181
ATR : 18447308 18447310 18447313
SMO : SELMODRAFT_129942(CER1-2) SELMODRAFT_230422(CER1-1)
SYY : SYNGTS_2252(sll0208)
SYT : SYNGTI_2251(sll0208)
SYS : SYNPCCN_2250(sll0208)
SYQ : SYNPCCP_2250(sll0208)
SYNC : CB0101_00310 CB0101_04550
CGC : Cyagr_0039 Cyagr_1038
CYN : Cyan7425_0398 Cyan7425_2986
PSER : ABRG53_3065 ABRG53_4148
PPSU : NO713_00869 NO713_02677
» show all
Taxonomy
Reference
Authors
Cheesbrough TM, Kolattukudy PE.
Title
Alkane biosynthesis by decarbonylation of aldehydes catalyzed by a particulate preparation from Pisum sativum.
Journal
Reference
Authors
Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB
Title
Microbial biosynthesis of alkanes.
Journal
Sequence
Reference
Authors
Warui DM, Li N, Norgaard H, Krebs C, Bollinger JM Jr, Booker SJ
Title
Detection of formate, rather than carbon monoxide, as the stoichiometric coproduct in conversion of fatty aldehydes to alkanes by a cyanobacterial aldehyde decarbonylase.
Journal
Sequence
Reference
Authors
Li N, Chang WC, Warui DM, Booker SJ, Krebs C, Bollinger JM Jr
Title
Evidence for only oxygenative cleavage of aldehydes to alk(a/e)nes and formate by cyanobacterial aldehyde decarbonylases.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 4.1.99.5
ExPASy - ENZYME nomenclature database: 4.1.99.5
LinkDB
All DBs