| Entry |
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| Name |
4-chlorobenzoate---CoA ligase
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| Class |
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
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| Sysname |
4-chlorobenzoate:CoA ligase
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| Reaction(IUBMB) |
4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate [RN: R03932]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Requires Mg2+. This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.
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| History |
EC 6.2.1.33 created 1999
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K14417 | 4-chlorobenzoate-CoA ligase |
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| Reference |
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| Authors |
Dunaway-Mariano D, Babbitt PC |
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| Title |
On the origins and functions of the enzymes of the 4-chlorobenzoate to 4-hydroxybenzoate converting pathway. |
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| Journal |
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| Reference |
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| Authors |
Loffler F, Muller R, Lingens F. |
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| Title |
Purification and properties of 4-halobenzoate-coenzyme A ligase from Pseudomonas sp. CBS3. |
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| Journal |
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| Reference |
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| Authors |
Chang KH, Liang PH, Beck W, Scholten JD, Dunaway-Mariano D |
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| Title |
Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 6.2.1.33 |
| ExPASy - ENZYME nomenclature database: | 6.2.1.33 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 6.2.1.33 |
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| LinkDB |
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