| Entry |
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| Name |
formate---dihydrofolate ligase;
formyltransferase, dihydrofolate;
dihydrofolate formyltransferase;
formyl dihydrofolate synthase
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| Class |
Ligases;
Forming carbon-nitrogen bonds;
Other carbon-nitrogen ligases
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| Sysname |
formate:dihydrofolate ligase (ADP-forming)
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| Reaction(IUBMB) |
ATP + formate + dihydrofolate = ADP + phosphate + 10-formyldihydrofolate [RN: R02238]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Not identical with EC 6.3.4.3 (formate---tetrahydrofolate ligase).
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| History |
EC 6.3.4.17 created 1992
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| Reference |
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| Authors |
Drake JC, Baram J, Allegra CJ. |
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| Title |
Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF-7 breast cancer cells. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 6.3.4.17 |
| ExPASy - ENZYME nomenclature database: | 6.3.4.17 |
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| LinkDB |
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