KEGG    Network variation - Thyroid cancer
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ENTRYnt06274
NameThyroid cancer
CategoryDisease view; Cancer
Pathwayhsa05216 Thyroid cancer
DiseaseH00032 Thyroid cancer
Display drug-target relation   disease type
ERK signaling
             D1,D2
 |
    
N00001    EGFEGFRGRB2SOSRASRAFMEKERKCCND1
             D1,D2
 |
  
N00009          TRK*RASRAFMEKERK
       D3,D4
 |
     D1,D2
 |
  
N00008          RET*RASRAFMEKERK
             D1,D2
 |
    
N00012            (KRAS*,NRAS*)RAFMEKERKCCND1
           D5,D6
 |
 D1,D2
 |
  
N00013              BRAF*MEKERK
 
WNT signaling
N00056    WNT(FZD+LRP5/6)(DVL+FRAT)(GSK3B+AXIN+APC)CTNNB1TCF/LEF(MYC,CCND1)
N00061          CDH1*CTNNB1TCF/LEF(MYC,CCND1)
 
Transcription
N00115    TP53*(CDKN1A,GADD45,BAX..
N00126    PAX8-PPARG(RXR+PPARG)


Drug name
D1D10176Trametinib dimethyl sulfoxide (JAN/USAN)
D2D10604Binimetinib (JAN/USAN/INN)
D3D11712Pralsetinib (USAN/INN)
D4D11713Selpercatinib (JAN/USAN/INN)
D5D10104Dabrafenib mesylate (USAN)
D6D11053Encorafenib (JAN/USAN/INN)