| Entry |
|
|---|
| Name |
Ciprofloxacin (JP18/USP/INN);
Cipro (TN);
Otiprio (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C17H18FN3O3
|
|---|
| Exact mass |
331.1332
|
|---|
| Mol weight |
331.34
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
|
|---|
| Remark |
| Therapeutic category: | 6241 |
| Product (DG00617): | D00186<JP/US> D02216<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Interaction |
CYP inhibition: CYP1A2 [HSA: 1544]
|
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| Structure map |
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| Other map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA02 Ciprofloxacin
D00186 Ciprofloxacin (JP18/USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AE Fluoroquinolones
S01AE03 Ciprofloxacin
D00186 Ciprofloxacin (JP18/USP/INN) <JP/US>
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA15 Ciprofloxacin
D00186 Ciprofloxacin (JP18/USP/INN) <JP/US>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03A ANTIINFECTIVES
S03AA Antiinfectives
S03AA07 Ciprofloxacin
D00186 Ciprofloxacin (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Quinolones
Ciprofloxacin
D00186 Ciprofloxacin (JP18/USP/INN)
Ophthalmic Agents
Ophthalmic Anti-Infectives
Antibacterials, Ophthalmic
Ciprofloxacin
D00186 Ciprofloxacin (JP18/USP/INN)
Otic Agents
Otic Anti-Infectives
Ciprofloxacin
D00186 Ciprofloxacin (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
624 Synthetic antibacterials
6241 Pyridonecarboxylic acids
D00186 Ciprofloxacin (JP18/USP/INN)
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00617 Ciprofloxacin
D00186 Ciprofloxacin
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00617 Ciprofloxacin
D00186 Ciprofloxacin
Drug classes [BR:br08332]
Antibacterial
DG01549 Fluoroquinolone
D00186 Ciprofloxacin
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
D00186 Ciprofloxacin (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00186 Ciprofloxacin
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00186
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00617 Ciprofloxacin
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00617 Ciprofloxacin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
DG00617 Ciprofloxacin
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 24
1 C8y C 19.6700 -6.0900
2 C8y C 19.6700 -7.4900
3 C8x C 20.8600 -8.1900
4 C8y C 22.1200 -7.4900
5 C8y C 22.1200 -6.0900
6 C8x C 20.8600 -5.3900
7 N4y N 23.3100 -8.1900
8 C8x C 24.5000 -7.4900
9 C8y C 24.5000 -6.0900
10 C8y C 23.3100 -5.3900
11 N1y N 18.4800 -8.1900
12 C1x C 17.2900 -7.4900
13 C1x C 16.0300 -8.1900
14 N1x N 16.0300 -9.5900
15 C1x C 17.2200 -10.2900
16 C1x C 18.4800 -9.5900
17 X F 18.4800 -5.3900
18 O5x O 23.3100 -3.9900
19 C6a C 25.6900 -5.3900
20 O6a O 26.8800 -6.0900
21 O6a O 25.6900 -3.9900
22 C1y C 23.3100 -9.5900
23 C1x C 24.0100 -10.7800
24 C1x C 22.6100 -10.7800
BOND 27
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 5 10 1
12 2 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 11 16 1
19 1 17 1
20 10 18 2
21 9 19 1
22 19 20 1
23 19 21 2
24 7 22 1
25 22 23 1
26 22 24 1
27 23 24 1
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