| Entry |
|
|---|
| Name |
Physostigmine (USP);
Eserine (TN) |
|---|
| Formula |
C15H21N3O2
|
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| Exact mass |
275.1634
|
|---|
| Mol weight |
275.3461
|
|---|
| Structure |
|
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| Simcomp |
|
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| Source |
Physostigma venenosum [TAX: 271807]
|
|---|
| Class |
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Acetylcholinesterase inhibitor (ophthalmic) |
|---|
| Comment |
Reversible cholinesterase inhibitor
|
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| Target |
|
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| Pathway |
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| Interaction |
|
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| Structure map |
| map07056 | Agents for Alzheimer-type dementia |
| map07220 | Cholinergic and anticholinergic drugs |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EB Parasympathomimetics
S01EB05 Physostigmine
D00196 Physostigmine (USP)
V VARIOUS
V03 ALL OTHER THERAPEUTIC PRODUCTS
V03A ALL OTHER THERAPEUTIC PRODUCTS
V03AB Antidotes
V03AB19 Physostigmine
D00196 Physostigmine (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG01132 Physostigmine
D00196 Physostigmine
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01132 Physostigmine
D00196 Physostigmine
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Carboxylic-ester hydrolases
ACHE
D00196 Physostigmine (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG01132 Physostigmine
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01132 Physostigmine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 20
1 C1z C 26.2112 -14.1214
2 C8y C 24.9526 -14.5409
3 C1y C 27.0503 -15.2402
4 C1x C 27.0503 -12.9326
5 C1a C 25.3721 -13.0026
6 C8y C 24.9526 -15.9395
7 C8x C 23.6939 -13.8417
8 N1y N 26.2112 -16.3591
9 N1y N 28.3789 -14.8206
10 C1x C 28.3789 -13.3522
11 C8x C 23.6939 -16.6388
12 C8y C 22.4353 -14.5409
13 C1a C 26.6308 -17.6877
14 C8x C 22.4353 -15.9395
15 O7a O 21.2465 -13.8417
16 C7a C 20.0578 -14.5409
17 N1b N 18.8690 -13.8417
18 O6a O 20.0578 -15.9395
19 C1a C 17.6103 -14.5409
20 C1a C 29.4977 -15.5899
BOND 22
1 16 17 1
2 16 18 2
3 17 19 1
4 6 8 1
5 9 10 1
6 12 14 1
7 1 2 1
8 1 3 1
9 1 4 1
10 1 5 1 #Up
11 2 6 2
12 2 7 1
13 3 8 1
14 3 9 1
15 4 10 1
16 6 11 1
17 7 12 2
18 8 13 1
19 11 14 2
20 12 15 1
21 15 16 1
22 9 20 1
|
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