KEGG   DRUG: スピロノラクトン
エントリ  
D00443                      Drug                                   
一般名   
スピロノラクトン (JP18);
Spironolactone (JP18/USP/INN)
商品名   
  後発品
米国の商品 
  後発品
SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (A-S Medication Solutions), SPIRONOLACTONE (ATLANTIC BIOLOGICALS CORP.), SPIRONOLACTONE (Accord Healthcare), SPIRONOLACTONE (American Health Packaging), SPIRONOLACTONE (Amneal Pharmaceuticals LLC), SPIRONOLACTONE (Amneal Pharmaceuticals NY LLC), SPIRONOLACTONE (Amneal Pharmaceuticals of New York LLC), SPIRONOLACTONE (Aphena Pharma Solutions - Tennessee), SPIRONOLACTONE (Aphena Pharma Solutions - Tennessee), SPIRONOLACTONE (Aphena Pharma Solutions - Tennessee), SPIRONOLACTONE (Aphena Pharma Solutions - Tennessee), SPIRONOLACTONE (Asclemed USA), SPIRONOLACTONE (Asclemed USA), SPIRONOLACTONE (Aurobindo Pharma Limited), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Bryant Ranch Prepack), SPIRONOLACTONE (Cardinal Health 107), SPIRONOLACTONE (Cardinal Health 107), SPIRONOLACTONE (Cardinal Health 107), SPIRONOLACTONE (Direct_Rx), SPIRONOLACTONE (Direct_Rx), SPIRONOLACTONE (Direct_Rx), SPIRONOLACTONE (Direct_Rx), SPIRONOLACTONE (Jubilant Cadista Pharmaceuticals), SPIRONOLACTONE (Major Pharmaceuticals), SPIRONOLACTONE (McKesson Corporation dba SKY Packaging), SPIRONOLACTONE (Mylan Institutional), SPIRONOLACTONE (Mylan Pharmaceuticals), SPIRONOLACTONE (NCS HealthCare of KY), SPIRONOLACTONE (NCS HealthCare of KY), SPIRONOLACTONE (NCS HealthCare of KY), SPIRONOLACTONE (NorthStar Rx LLC), SPIRONOLACTONE (NorthStar Rx LLC), SPIRONOLACTONE (NorthStar RxLLC), SPIRONOLACTONE (Northwind Pharmaceuticals), SPIRONOLACTONE (Northwind Pharmaceuticals), SPIRONOLACTONE (Northwind Pharmaceuticals), SPIRONOLACTONE (Northwind Pharmaceuticals), SPIRONOLACTONE (NuCare Pharmaceuticals), SPIRONOLACTONE (NuCare Pharmaceuticals), SPIRONOLACTONE (NuCare Pharmaceuticals), SPIRONOLACTONE (NuCare Pharmaceuticals), SPIRONOLACTONE (NuCare Pharmaceuticals), SPIRONOLACTONE (NuCare Pharmaceuticals), SPIRONOLACTONE (NuCare Pharmaceuticals), SPIRONOLACTONE (Oxford Pharmaceuticals), SPIRONOLACTONE (PD-Rx Pharmaceuticals), SPIRONOLACTONE (PD-Rx Pharmaceuticals), SPIRONOLACTONE (PD-Rx Pharmaceuticals), SPIRONOLACTONE (PD-Rx Pharmaceuticals), SPIRONOLACTONE (PD-Rx Pharmaceuticals), SPIRONOLACTONE (PD-Rx Pharmaceuticals), SPIRONOLACTONE (Padagis US LLC), SPIRONOLACTONE (PharmPak), SPIRONOLACTONE (Preferred Pharmaceuticals Inc..), SPIRONOLACTONE (Preferred Pharmaceuticals), SPIRONOLACTONE (Preferred Pharmaceuticals), SPIRONOLACTONE (Preferred Pharmaceuticals), SPIRONOLACTONE (Preferred Pharmaceuticals), SPIRONOLACTONE (Preferred Pharmaceuticals), SPIRONOLACTONE (Proficient Rx LP), SPIRONOLACTONE (Proficient Rx LP), SPIRONOLACTONE (Proficient Rx LP), SPIRONOLACTONE (Proficient Rx LP), SPIRONOLACTONE (Proficient Rx LP), SPIRONOLACTONE (Proficient Rx LP), SPIRONOLACTONE (QPharma), SPIRONOLACTONE (QPharma), SPIRONOLACTONE (Quality Care Products), SPIRONOLACTONE (Quality Care Products), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (REMEDYREPACK), SPIRONOLACTONE (RPK Pharmaceuticals), SPIRONOLACTONE (RPK Pharmaceuticals), SPIRONOLACTONE (RPK Pharmaceuticals), SPIRONOLACTONE (RPK Pharmaceuticals), SPIRONOLACTONE (RPK Pharmaceuticals), SPIRONOLACTONE (RPK Pharmaceuticals), SPIRONOLACTONE (RPK Pharmaceuticals), SPIRONOLACTONE (Sun Pharmaceutical Industries), SPIRONOLACTONE (Zydus Lifesciences Limited), SPIRONOLACTONE (Zydus Pharmaceuticals (USA))
組成式   
C24H32O4S
質量    
416.2021
分子量   
416.5735
構造式   
Simcomp   
クラス   
心血管系用薬
 DG03231  血圧降下薬
  DG01676  アルドステロン拮抗薬
 DG01885  カリウム保持性利尿薬
コード   
同一コード: C07310
薬効分類: 2133
ATCコード: C03DA01
商品: D00443<JP/US>
商品 (mixture): D10270<US>
効能    
血圧降下薬, 利尿薬, アルドステロン拮抗薬
  疾患
高血圧症 [DS:H01633]
原発性アルドステロン症 [DS:H01603]
ターゲット 
NR3C2 (MR) [HSA:4306] [KO:K08555]
  パスウェイ
hsa04960  アルドステロンの調節によるナトリウムの再吸収
相互作用  

構造マップ 
map07225  糖質コルチコイド・鉱質コルチコイド受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   213  利尿剤
    2133  抗アルドステロン製剤;トリアムテレン等
     D00443  スピロノラクトン (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C03 利尿薬
   C03D アルドステロン拮抗薬とその他のカリウム保持剤
    C03DA アルドステロン拮抗薬
     C03DA01 スピロノラクトン
      D00443  スピロノラクトン (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  ミネラルコルチコイド受容体拮抗薬
   スピロノラクトン
    D00443  スピロノラクトン (JP18)
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG03231  血圧降下薬
   DG01676  アルドステロン拮抗薬
    D00443  スピロノラクトン
  DG01885  カリウム保持性利尿薬
   D00443  スピロノラクトン
医薬品クラス [BR:jp08332]
 心血管系用薬
  DG01676  アルドステロン拮抗薬 [商品一覧]
   D00443  スピロノラクトン
  DG03231  血圧降下薬 [商品一覧]
   D00443  スピロノラクトン
ターゲットに基づく医薬品分類 [BR:jp08310]
 核内受容体
  エストロゲン様受容体
   3-ケトステロイド受容体
    NR3C2 (MR)
     D00443  スピロノラクトン (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00443  スピロノラクトン
  D00443  スピロノラクトン錠
リンク   
CAS: 52-01-7
PubChem: 7847509
PDB-CCD: SNL[PDBj]
LigandBox: D00443
日化辞: J4.474A
LinkDB    

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