| Entry |
|
|---|
| Name |
Oxaprozin (JP19/USP/INN);
Daypro (TN) |
|---|
| Product |
|
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| Generic |
|
|---|
| Formula |
C18H15NO3
|
|---|
| Exact mass |
293.1052
|
|---|
| Mol weight |
293.32
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivative
|
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| Remark |
| Therapeutic category: | 1149 |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, COX inhibitor |
|---|
| Disease |
Rheumatoid arthritis [DS: H00630] Juvenile rheumatoid arthritis [DS: H01672] |
|---|
| Comment |
Propionic acid derivative
|
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| Target |
|
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| Pathway |
|
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| Interaction |
|
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| Structure map |
| map07112 | 1,2-Diphenyl substitution family |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE12 Oxaprozin
D00463 Oxaprozin (JP19/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Oxaprozin
D00463 Oxaprozin (JP19/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1149 Others
D00463 Oxaprozin (JP19/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivative
D00463 Oxaprozin
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00463 Oxaprozin
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00463 Oxaprozin (JP19/USP/INN) <JP/US>
PTGS2 (COX2)
D00463 Oxaprozin (JP19/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00463 Oxaprozin
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 22
1 C8y C 25.8557 -17.0142
2 C1b C 27.2577 -17.0142
3 N5x N 25.0145 -15.8927
4 C8y C 23.7060 -16.3132
5 C8y C 23.7060 -17.7152
6 O2x O 25.0145 -18.1358
7 C8x C 20.0609 -14.2103
8 C8x C 20.0609 -15.6123
9 C8x C 21.2760 -16.3132
10 C8y C 22.4910 -15.6123
11 C8x C 22.4910 -14.2103
12 C8x C 21.2760 -13.5093
13 C8x C 20.0609 -18.4162
14 C8x C 20.0609 -19.8181
15 C8x C 21.2760 -20.5191
16 C8x C 22.4910 -19.8181
17 C8y C 22.4910 -18.4162
18 C8x C 21.2760 -17.7152
19 C1b C 27.9586 -15.8000
20 C6a C 29.3606 -15.8000
21 O6a O 30.0620 -14.5852
22 O6a O 30.0612 -17.0135
BOND 24
1 1 2 1
2 1 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 7 8 2
8 8 9 1
9 9 10 2
10 10 11 1
11 11 12 2
12 7 12 1
13 10 4 1
14 13 14 2
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 2
19 13 18 1
20 17 5 1
21 2 19 1
22 19 20 1
23 20 21 1
24 20 22 2
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