| Entry |
|
|---|
| Name |
Hydromorphone hydrochloride (JAN/USP);
Dilaudid (TN);
Exalgo (TN);
Palladone (TN) |
|---|
| Product |
|
|---|
| Generic |
HYDROMORPHONE HYDROCHLORIDE (American Health Packaging), HYDROMORPHONE HYDROCHLORIDE (American Health Packaging), HYDROMORPHONE HYDROCHLORIDE (Ascent Pharmaceuticals), HYDROMORPHONE HYDROCHLORIDE (Aurolife Pharma), HYDROMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), HYDROMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), HYDROMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), HYDROMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), HYDROMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), HYDROMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), HYDROMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), HYDROMORPHONE HYDROCHLORIDE (Camber Pharmaceuticals), HYDROMORPHONE HYDROCHLORIDE (Hikma Pharmaceuticals USA), HYDROMORPHONE HYDROCHLORIDE (Hikma Pharmaceuticals USA), HYDROMORPHONE HYDROCHLORIDE (Hospira), HYDROMORPHONE HYDROCHLORIDE (Padagis US LLC), HYDROMORPHONE HYDROCHLORIDE (Rhodes Pharmaceuticals L.P.), HYDROMORPHONE HYDROCHLORIDE (SpecGx LLC), HYDROMORPHONE HYDROCHLORIDE (Teva Parenteral Medicines), HYDROMORPHONE HYDROCHLORIDE (Trigen Laboratories), HYDROMORPHONE HYDROCHLORIDE (XLCare Pharmaceuticals) |
|---|
| Formula |
C17H19NO3. HCl
|
|---|
| Exact mass |
321.1132
|
|---|
| Mol weight |
321.7986
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
Metabolizing enzyme substrate
DG02924 UGT substrate
|
|---|
| Remark |
| Therapeutic category: | 8119 |
| Product (DG00811): | D00839<JP/US> |
|
|---|
| Efficacy |
Analgesic (narcotic), Opioid receptor agonist |
|---|
| Comment |
Opium alkaloid
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AA Natural opium alkaloids
N02AA03 Hydromorphone
D00839 Hydromorphone hydrochloride (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Analgesics
Opioid Analgesics, Long-acting
Hydromorphone
D00839 Hydromorphone hydrochloride (JAN/USP)
Opioid Analgesics, Short-acting
Hydromorphone
D00839 Hydromorphone hydrochloride (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
8 Narcotics
81 Alkaloidal narcotics
811 Opium alkaloids
8119 Others
D00839 Hydromorphone hydrochloride (JAN/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00811 Hydromorphone
D00839 Hydromorphone hydrochloride
Analgesic
DG01984 Opioid analgesics
DG00811 Hydromorphone
D00839 Hydromorphone hydrochloride
Metabolizing enzyme substrate
DG02924 UGT substrate
DG00811 Hydromorphone
D00839 Hydromorphone hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D00839 Hydromorphone hydrochloride (JAN/USP) <JP/US>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00839
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00839
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG00811 Hydromorphone
Analgesic
DG01984 Opioid analgesics
DG00811 Hydromorphone
Metabolizing enzyme substrate
DG02924 UGT substrate
DG00811 Hydromorphone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 X Cl 33.7684 -12.5160
2 C1z C 26.4194 -13.3594
3 C8y C 26.4194 -12.0354
4 C1y C 27.6040 -14.0561
5 C1y C 25.3045 -13.9865
6 C1x C 27.6040 -12.7323
7 C8y C 25.3045 -11.4083
8 C8y C 27.6040 -11.4083
9 C1y C 28.7189 -13.3594
10 C1x C 27.6040 -15.3104
11 O2x O 23.9806 -12.6625
12 C5x C 25.3045 -15.3104
13 C1x C 29.8337 -12.7323
14 C8y C 25.3045 -10.0844
15 C1x C 28.7189 -12.1051
16 C8x C 27.6040 -10.0844
17 N1y N 29.8337 -14.0561
18 C1x C 26.4194 -16.0072
19 O5x O 24.1897 -16.0072
20 C8x C 26.4891 -9.4573
21 O1a O 24.1897 -9.4573
22 C1a C 31.2326 -14.0561
BOND 25
1 2 3 1
2 2 4 1
3 2 5 1
4 2 6 1 #Up
5 3 7 2
6 3 8 1
7 4 9 1
8 4 10 1
9 5 11 1 #Down
10 5 12 1
11 6 13 1
12 7 14 1
13 8 15 1
14 8 16 2
15 9 17 1 #Up
16 10 18 1
17 12 19 2
18 14 20 2
19 14 21 1
20 7 11 1
21 9 15 1
22 12 18 1
23 13 17 1
24 16 20 1
25 17 22 1
|
|---|
