| Entry |
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| Name |
Cefuroxime axetil (JP18/USP/INN);
Ceftin (TN) |
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| Product |
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| Generic |
CEFUROXIME AXETIL (A-S Medication Solutions), CEFUROXIME AXETIL (A-S Medication Solutions), CEFUROXIME AXETIL (A-S Medication Solutions), CEFUROXIME AXETIL (A-S Medication Solutions), CEFUROXIME AXETIL (American Health Packaging), CEFUROXIME AXETIL (Ascend Laboratories), CEFUROXIME AXETIL (Aurobindo Pharma Limited), CEFUROXIME AXETIL (Bryant Ranch Prepack), CEFUROXIME AXETIL (Bryant Ranch Prepack), CEFUROXIME AXETIL (Bryant Ranch Prepack), CEFUROXIME AXETIL (Bryant Ranch Prepack), CEFUROXIME AXETIL (Direct_Rx), CEFUROXIME AXETIL (Golden State Medical Supply), CEFUROXIME AXETIL (Lupin Pharmaceuticals), CEFUROXIME AXETIL (NorthStar Rx LLC), CEFUROXIME AXETIL (NuCare Pharmaceuticals), CEFUROXIME AXETIL (NuCare Pharmaceuticals), CEFUROXIME AXETIL (NuCare Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (Proficient Rx LP), CEFUROXIME AXETIL (REMEDYREPACK), CEFUROXIME AXETIL (RPK Pharmaceuticals), CEFUROXIME AXETIL (RPK Pharmaceuticals), CEFUROXIME AXETIL (Redpharm Drug), CEFUROXIME AXETIL (Redpharm Drug), CEFUROXIME AXETIL (Rising Health) |
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| Formula |
C20H22N4O10S
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| Exact mass |
510.1057
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| Mol weight |
510.4745
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Therapeutic category: | 6132 |
| Product (DG00558): | D00914<JP/US> D00915<US> |
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
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| Disease |
Uncomplicated urinary tract infections [DS: H01176] Gonorrhea [DS: H00315] Lyme disease [DS: H00353] |
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| Comment |
Active form of prodrug: Cefuroxime [DR: D00262]
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| Target |
penicillin binding protein |
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| Pathway |
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| Interaction |
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| Structure map |
| map07012 | Cephalosporins - parenteral agents |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DC Second-generation cephalosporins
J01DC02 Cefuroxime
D00914 Cefuroxime axetil (JP18/USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA27 Cefuroxime
D00914 Cefuroxime axetil (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Beta-lactam, Cephalosporins
Cefuroxime
D00914 Cefuroxime axetil (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D00914 Cefuroxime axetil (JP18/USP/INN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00558 Cefuroxime
D00914 Cefuroxime axetil
DG01775 Second-generation cephalosporin
DG00558 Cefuroxime
D00914 Cefuroxime axetil
DG01804 Oxyimino beta-lactam
DG00558 Cefuroxime
D00914 Cefuroxime axetil
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D00914 Cefuroxime axetil
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
D00914 Cefuroxime axetil (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00914 Cefuroxime axetil
Prodrugs [br08324.html]
D00914
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00558 Cefuroxime
DG01775 Second-generation cephalosporin
DG00558 Cefuroxime
DG01804 Oxyimino beta-lactam
DG00558 Cefuroxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
DG00558 Cefuroxime
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 35
1 C1y C 32.4830 -17.3815
2 N1y N 32.4830 -18.7522
3 C2y C 33.6704 -19.4375
4 C2y C 34.8574 -18.7522
5 C1x C 34.8574 -17.3815
6 S2x S 33.6704 -16.6961
7 C1y C 31.1122 -17.3815
8 C5x C 31.1122 -18.7522
9 N1b N 29.9252 -16.6961
10 C5a C 28.7380 -17.3815
11 O5a O 28.7380 -18.7522
12 O5x O 29.9252 -19.4375
13 C2c C 27.5508 -16.6961
14 C1b C 36.0626 -19.4485
15 C7a C 33.6704 -21.8391
16 O7a O 32.4665 -22.5342
17 O6a O 34.8407 -22.5150
18 C8y C 26.3447 -17.3929
19 O2x O 25.2137 -16.5965
20 C8x C 24.1023 -17.4263
21 C8x C 24.5479 -18.7397
22 C8x C 25.9347 -18.7220
23 N2b N 27.5507 -15.3044
24 O7a O 37.2666 -18.7539
25 C7a C 38.4302 -19.4263
26 N1a N 39.6019 -18.7501
27 O6a O 38.4298 -20.8040
28 C1c C 31.2867 -21.8527
29 O7a O 30.1305 -22.5200
30 C7a C 28.9560 -21.8415
31 C1a C 27.7902 -22.5142
32 C1a C 31.2864 -20.4575
33 O6a O 28.9562 -20.4574
34 O2a O 28.7734 -14.5979
35 C1a C 28.7734 -13.1979
BOND 37
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 3 15 1
17 15 16 1
18 15 17 2
19 13 18 1
20 18 19 1
21 19 20 1
22 20 21 2
23 21 22 1
24 18 22 2
25 13 23 2
26 14 24 1
27 24 25 1
28 25 26 1
29 25 27 2
30 16 28 1
31 28 29 1
32 29 30 1
33 30 31 1
34 28 32 1
35 30 33 2
36 23 34 1
37 34 35 1
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