KEGG   DRUG: Fosfomycin tromethamine
Entry
D00925                      Drug                                   
Name
Fosfomycin tromethamine (USP);
Monurol (TN)
Product
  Generic
Formula
C3H7O4P. C4H11NO3
Exact mass
259.0821
Mol weight
259.1941
Structure
Remark
ATC code: J01XX01 S02AA17
Chemical structure group: DG00633
Product (DG00633): D00925<US> D02187<JP> D02188<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
UDP-N-acetylglucosamine 1-carboxyvinyltransferase [KO:K00790]
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XX Other antibacterials
     J01XX01 Fosfomycin
      D00925  Fosfomycin tromethamine (USP) <US>
 S SENSORY ORGANS
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA17 Fosfomycin
      D00925  Fosfomycin tromethamine (USP) <US>
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Fosfomycin
    D00925  Fosfomycin tromethamine (USP)
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, other
   Other peptidoglycan biosynthesis inhibitor
    D00925  Fosfomycin tromethamine (USP) <US>
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, other
   Other peptidoglycan biosynthesis inhibitor
    DG00633  Fosfomycin
Other DBs
CAS: 78964-85-9
PubChem: 7847988
ChEBI: 5162
LigandBox: D00925
NIKKAJI: J321.566K
LinkDB
KCF data

ATOM        16
            1   C1y C    24.4300  -17.6400
            2   C1y C    25.7600  -17.6400
            3   O2x O    25.0600  -16.4500
            4   P1b P    23.2400  -18.4100
            5   C1a C    26.9500  -18.4100
            6   O1c O    21.9800  -19.1100
            7   O1c O    22.5400  -17.1500
            8   O1c O    23.9400  -19.6000
            9   C1d C    32.6782  -18.3810
            10  C1b C    31.5325  -17.7204
            11  C1b C    32.6782  -19.7313
            12  C1b C    33.8240  -17.7379
            13  N1a N    32.7193  -16.5512
            14  O1a O    30.3867  -18.3810
            15  O1a O    33.8240  -20.3919
            16  O1a O    34.9873  -18.3985
BOND        15
            1     1   2 1
            2     2   3 1
            3     3   1 1
            4     1   4 1 #Up
            5     2   5 1 #Up
            6     4   6 2
            7     4   7 1
            8     4   8 1
            9     9  10 1
            10    9  11 1
            11    9  12 1
            12    9  13 1
            13   10  14 1
            14   11  15 1
            15   12  16 1

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