| Entry |
|
|---|
| Name |
Pazufloxacin (JAN/INN) |
|---|
| Formula |
C16H15FN2O4
|
|---|
| Exact mass |
318.1016
|
|---|
| Mol weight |
318.2997
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
|
|---|
| Remark |
| Product (DG00629): | D05382<JP> |
|
|---|
| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
|---|
| Target |
|
|---|
| Interaction |
CYP inhibition: CYP1A2 [HSA: 1544]
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA18 Pazufloxacin
D01153 Pazufloxacin (JAN/INN)
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00629 Pazufloxacin
D01153 Pazufloxacin
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00629 Pazufloxacin
D01153 Pazufloxacin
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
D01153 Pazufloxacin (JAN/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D01153
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG01549 Fluoroquinolone
DG00629 Pazufloxacin
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00629 Pazufloxacin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Fluoroquinolone
DG00629 Pazufloxacin
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 23
1 C1x C 20.3263 -21.4450
2 C1z C 21.0246 -20.1880
3 C1x C 21.7229 -21.4450
4 C8y C 22.2117 -19.4898
5 N1a N 19.8375 -19.4898
6 O2x O 23.3988 -21.6544
7 C1y C 25.7730 -21.6544
8 C1x C 24.5859 -22.3527
9 C8y C 23.3988 -20.2579
10 C8y C 22.2117 -18.0932
11 C8x C 23.3988 -17.3949
12 N4y N 25.7730 -20.2579
13 C8y C 24.5859 -19.5596
14 C8y C 24.5859 -18.1630
15 C8y C 25.7730 -17.4647
16 C8y C 27.0299 -18.1630
17 C8x C 27.0299 -19.5596
18 C6a C 28.2170 -17.4647
19 O6a O 28.2170 -16.0681
20 O6a O 29.4041 -18.1630
21 O5x O 25.7730 -16.0681
22 X F 20.9548 -17.3949
23 C1a C 27.0299 -22.3527
BOND 26
1 4 10 1
2 10 11 2
3 11 14 1
4 1 3 1
5 3 2 1
6 6 9 1
7 12 7 1
8 7 8 1
9 12 13 1
10 13 14 2
11 14 15 1
12 15 16 1
13 16 17 2
14 17 12 1
15 8 6 1
16 16 18 1
17 4 2 1
18 18 19 2
19 1 2 1
20 18 20 1
21 2 5 1
22 15 21 2
23 13 9 1
24 10 22 1
25 9 4 2
26 7 23 1 #Up
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