| Entry |
|
|---|
| Name |
Trimebutine maleate (JP18);
Cerekinon (TN) |
|---|
| Formula |
C22H29NO5. C4H4O4
|
|---|
| Exact mass |
503.2155
|
|---|
| Mol weight |
503.5415
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Analgesic
DG01587 Opioid receptor agonist/antagonist
|
|---|
| Remark |
| Therapeutic category: | 2399 |
| Product (DG00031): | D01500<JP> |
|
|---|
| Efficacy |
Antispasmodic |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03AA Synthetic anticholinergics, esters with tertiary amino group
A03AA05 Trimebutine
D01500 Trimebutine maleate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
23 Digestive organ agents
239 Miscellaneous
2399 Others
D01500 Trimebutine maleate (JP18)
Classification of Japanese OTC drugs [BR:br08313]
Agents for digestive organs
20 Other drugs for digestive organs
D01500 Trimebutine maleate (JP18)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Trimebutine
D01500 Trimebutine maleate (JP18)
Drug groups [BR:br08330]
Analgesic
DG01587 Opioid receptor agonist/antagonist
DG00031 Trimebutine
D01500 Trimebutine maleate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D01500 Trimebutine maleate (JP18) <JP>
OPRK1
D01500 Trimebutine maleate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01500 Trimebutine maleate
Rx-to-OTC switch list in Japan [br08314.html]
D01500
Drug groups [BR:br08330]
Analgesic
DG01587 Opioid receptor agonist/antagonist
DG00031 Trimebutine
|
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| Other DBs |
|
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| LinkDB |
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| KCF data |
ATOM 36
1 C6a C 31.2900 -21.2800
2 C2b C 30.6600 -20.0900
3 O6a O 30.7300 -22.4700
4 O6a O 32.6900 -21.2800
5 C2b C 29.0500 -20.0900
6 C6a C 28.3500 -21.2800
7 O6a O 27.0200 -21.2800
8 O6a O 29.0500 -22.4700
9 C8y C 18.7600 -22.0500
10 C8x C 18.7600 -20.6500
11 C8y C 20.0200 -19.9500
12 C8y C 21.2100 -20.6500
13 C8y C 21.2100 -22.0500
14 C8x C 20.0200 -22.7500
15 O2a O 22.4700 -19.9500
16 C1a C 23.6600 -20.6500
17 O2a O 20.0200 -18.4800
18 C1a C 21.2100 -17.7800
19 O2a O 22.4700 -22.7500
20 C1a C 22.4700 -24.1500
21 C7a C 17.5700 -22.7500
22 O7a O 16.3800 -22.0500
23 C1b C 15.1200 -22.7500
24 O6a O 17.5700 -24.1500
25 C1d C 13.9193 -22.0301
26 N1c N 12.6954 -22.7100
27 C1a C 11.4626 -21.9713
28 C1a C 12.6724 -24.0800
29 C8y C 13.9193 -20.6301
30 C1b C 13.9193 -23.4301
31 C1a C 15.1200 -24.1500
32 C8x C 15.1310 -19.9305
33 C8x C 15.1310 -18.5305
34 C8x C 13.9186 -17.8305
35 C8x C 12.7069 -18.5301
36 C8x C 12.7069 -19.9301
BOND 36
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 5 6 1
6 6 7 1
7 6 8 2
8 9 10 2
9 10 11 1
10 12 15 1
11 11 12 2
12 15 16 1
13 13 19 1
14 19 20 1
15 12 13 1
16 9 21 1
17 11 17 1
18 21 22 1
19 13 14 2
20 22 23 1
21 17 18 1
22 14 9 1
23 21 24 2
24 23 25 1
25 25 26 1
26 26 27 1
27 26 28 1
28 25 29 1
29 25 30 1
30 30 31 1
31 29 32 1
32 32 33 2
33 33 34 1
34 34 35 2
35 35 36 1
36 29 36 2
|
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