| Entry |
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| Name |
Pipemidic acid hydrate (JP18);
Karunomazin (TN) |
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| Formula |
C14H17N5O3. 3H2O
|
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| Exact mass |
357.1648
|
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| Mol weight |
357.3623
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| Structure |
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| Simcomp |
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| Class |
Antibacterial
DG01550 Quinolone
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
|
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| Remark |
|
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| Efficacy |
Antibacterial, Nucleic acid biosynthesis inhibitor |
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| Target |
|
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| Interaction |
CYP inhibition: CYP1A2 [HSA: 1544]
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MB Other quinolones
J01MB04 Pipemidic acid
D01531 Pipemidic acid hydrate (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG00631 Pipemidic acid
D01531 Pipemidic acid hydrate
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00631 Pipemidic acid
D01531 Pipemidic acid hydrate
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Other quinolone
D01531 Pipemidic acid hydrate (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01531 Pipemidic acid hydrate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D01531
Drug groups [BR:br08330]
Antibacterial
DG01550 Quinolone
DG00631 Pipemidic acid
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00631 Pipemidic acid
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Nucleic acid synthesis inhibitor
Other quinolone
DG00631 Pipemidic acid
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 N5x N 19.7420 -18.1466
2 C8y C 19.7420 -19.5478
3 N5x N 20.9525 -20.2450
4 C8x C 20.9525 -17.4423
5 C8y C 22.1629 -18.1466
6 C8y C 22.1570 -19.5478
7 N4y N 23.3685 -20.2503
8 C8x C 24.5860 -19.5582
9 C8y C 24.5921 -18.1569
10 C8y C 23.3805 -17.4476
11 O5x O 23.3864 -16.0461
12 C6a C 25.8095 -17.4579
13 O6a O 27.0211 -18.1672
14 O6a O 25.8156 -16.0564
15 N1y N 18.5279 -20.2457
16 C1b C 23.3626 -21.6446
17 C1a C 22.1521 -22.3365
18 C1x C 17.3193 -19.5396
19 C1x C 16.1051 -20.2372
20 N1x N 16.1024 -21.6377
21 C1x C 17.3137 -22.3404
22 C1x C 18.5279 -21.6426
23 O0 O 31.7128 -19.3648
24 O0 O 31.7128 -19.3648
25 O0 O 31.7128 -19.3648
BOND 24
1 9 12 1
2 12 13 1
3 1 2 1
4 12 14 2
5 2 3 2
6 2 15 1
7 3 6 1
8 7 16 1
9 5 4 1
10 16 17 1
11 5 6 2
12 6 7 1
13 7 8 1
14 8 9 2
15 9 10 1
16 15 18 1
17 18 19 1
18 19 20 1
19 20 21 1
20 21 22 1
21 22 15 1
22 10 5 1
23 4 1 2
24 10 11 2
BRACKET 1 29.8900 -20.4400 29.8900 -18.3400
1 32.3400 -18.3400 32.3400 -20.4400
1 3
ORIGINAL 1 23
REPEAT 1 24 25
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