| Entry |
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| Name |
Cefcapene pivoxil hydrochloride hydrate (JP18);
S 1108;
Flomox (TN) |
|---|
| Formula |
C23H29N5O8S2. HCl. H2O
|
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| Exact mass |
621.133
|
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| Mol weight |
622.1113
|
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Therapeutic category: | 6132 |
| Product (DG00585): | D01680<JP> |
|
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| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Comment |
Active form of prodrug: Cefcapene [DR: D07638]
|
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| Target |
penicillin binding protein |
|---|
| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD17 Cefcapene
D01680 Cefcapene pivoxil hydrochloride hydrate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D01680 Cefcapene pivoxil hydrochloride hydrate (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00585 Cefcapene
D01680 Cefcapene pivoxil hydrochloride hydrate
DG01776 Third-generation cephalosporin
DG00585 Cefcapene
D01680 Cefcapene pivoxil hydrochloride hydrate
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D01680 Cefcapene pivoxil hydrochloride hydrate
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D01680 Cefcapene pivoxil hydrochloride hydrate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01680 Cefcapene pivoxil hydrochloride hydrate
D01680 Cefcapene pivoxil hydrochloride tablets
D01680 Cefcapene pivoxil hydrochloride fine granules
Prodrugs [br08324.html]
D01680
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00585 Cefcapene
DG01776 Third-generation cephalosporin
DG00585 Cefcapene
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG00585 Cefcapene
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 40
1 C1y C 25.7895 -18.0565
2 N1y N 25.7895 -19.4438
3 C2y C 26.9911 -20.1372
4 C2y C 28.1924 -19.4438
5 C1x C 28.1924 -18.0565
6 S2x S 26.9911 -17.3629
7 C1y C 24.4023 -18.0565
8 C5x C 24.4023 -19.4438
9 N1b N 23.2011 -17.3629
10 C5a C 21.9995 -18.0565
11 O5a O 21.9995 -19.4438
12 O5x O 23.2011 -20.1372
13 C2c C 20.7981 -17.3629
14 C1b C 29.4122 -20.1483
15 C8y C 19.5773 -18.0681
16 O7a O 30.6186 -19.4521
17 C7a C 31.8196 -20.1459
18 C8x C 18.4326 -17.2621
19 S2x S 17.3078 -18.1019
20 C8y C 17.7588 -19.4311
21 N5x N 19.1624 -19.4131
22 N1a N 33.0574 -19.4314
23 O6a O 31.8198 -21.5197
24 C7a C 26.9910 -21.8681
25 O7a O 25.7799 -22.5672
26 O6a O 28.1900 -22.5602
27 C1b C 24.5888 -21.8793
28 O7a O 23.4100 -22.5596
29 C7a C 22.2255 -21.8755
30 C1d C 21.0435 -22.5577
31 O6a O 22.2255 -20.4769
32 C1a C 19.8385 -23.2535
33 C1a C 20.3571 -21.3683
34 C1a C 21.7480 -23.7785
35 C2b C 20.7980 -15.9542
36 N1a N 16.9265 -20.5677
37 C1b C 22.0019 -15.2590
38 C1a C 22.0019 -13.8590
39 X Cl 30.3226 -22.9812
40 O0 O 33.3142 -22.9116
BOND 40
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 14 16 1
18 16 17 1
19 15 18 2
20 18 19 1
21 19 20 1
22 20 21 2
23 15 21 1
24 17 22 1
25 17 23 2
26 3 24 1
27 24 25 1
28 24 26 2
29 25 27 1
30 27 28 1
31 28 29 1
32 29 30 1
33 29 31 2
34 30 32 1
35 30 33 1
36 30 34 1
37 13 35 2
38 20 36 1
39 35 37 1
40 37 38 1
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