| Entry |
|
|---|
| Name |
Cefteram pivoxil (JP18);
T 2588;
Tomiron (TN) |
|---|
| Formula |
C22H27N9O7S2
|
|---|
| Exact mass |
593.1475
|
|---|
| Mol weight |
593.6359
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 6132 |
| Product (DG01208): | D01686<JP> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Comment |
Active form of prodrug: Cefteram [DR: D07655]
|
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DD Third-generation cephalosporins
J01DD18 Cefteram
D01686 Cefteram pivoxil (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6132 Cephem antibioitics
D01686 Cefteram pivoxil (JP18)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG01208 Cefteram
D01686 Cefteram pivoxil
DG01804 Oxyimino beta-lactam
DG01208 Cefteram
D01686 Cefteram pivoxil
Drug classes [BR:br08332]
Antibacterial
DG01488 Cephem
D01686 Cefteram pivoxil
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
D01686 Cefteram pivoxil (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01686 Cefteram pivoxil
D01686 Cefteram pivoxil tablets
D01686 Cefteram pivoxil fine granules
Prodrugs [br08324.html]
D01686
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG01208 Cefteram
DG01804 Oxyimino beta-lactam
DG01208 Cefteram
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Third-generation cephalosporin
DG01208 Cefteram
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 40
1 C1y C 25.4403 -17.6462
2 N1y N 25.4403 -19.0212
3 C2y C 26.6090 -19.7087
4 C2y C 27.7778 -19.0212
5 C1x C 27.7778 -17.6462
6 S2x S 26.6090 -16.9587
7 C1y C 24.0652 -17.6462
8 C5x C 24.0652 -19.0212
9 N1b N 22.8277 -16.9587
10 C5a C 21.6590 -17.6462
11 O5a O 21.6590 -19.0212
12 O5x O 22.8277 -19.7087
13 C2c C 20.4901 -16.9587
14 C1b C 29.0153 -19.7087
15 C8y C 19.2526 -17.6462
16 N4y N 30.1842 -19.0212
17 C8x C 18.2214 -16.8211
18 S2x S 17.0526 -17.5774
19 C8y C 17.4652 -18.9524
20 N5x N 18.8401 -18.9524
21 N2b N 20.4901 -15.5836
22 C7a C 26.6090 -22.1835
23 O7a O 27.7778 -22.8711
24 O6a O 25.3715 -22.8711
25 N1a N 16.6401 -20.0524
26 N5x N 31.3135 -19.8099
27 C8y C 32.4136 -18.9822
28 N5x N 31.9664 -17.6801
29 N5x N 30.5899 -17.7031
30 C1a C 33.6042 -19.6695
31 C1b C 28.9720 -22.1944
32 O7a O 30.1291 -22.8752
33 C7a C 31.3142 -22.2038
34 C1d C 32.5138 -22.9099
35 O6a O 31.3252 -20.8066
36 C1a C 33.7045 -23.5973
37 C1a C 31.8101 -24.1165
38 C1a C 33.1952 -21.7417
39 O2a O 21.7086 -14.8865
40 C1a C 21.7086 -13.4865
BOND 43
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 13 15 1
17 14 16 1
18 15 17 2
19 17 18 1
20 18 19 1
21 19 20 2
22 15 20 1
23 13 21 2
24 3 22 1
25 22 23 1
26 22 24 2
27 19 25 1
28 16 26 1
29 26 27 2
30 27 28 1
31 28 29 2
32 16 29 1
33 27 30 1
34 23 31 1
35 31 32 1
36 32 33 1
37 33 34 1
38 33 35 2
39 34 36 1
40 34 37 1
41 34 38 1
42 21 39 1
43 39 40 1
|
|---|
