KEGG   DRUG: Glyclopyramide
Entry
D01799                      Drug                                   
Name
Glyclopyramide (JAN/INN);
Deamelin-S (TN)
Formula
C11H14ClN3O3S
Exact mass
303.0444
Mol weight
303.7652
Structure
Class
Antidiabetic agent
 DG01508  Sulfonylurea receptor agonist
  DG01734  Sulfonylurea
 DG02044  Hypoglycemic agent
  DG01734  Sulfonylurea
Remark
Therapeutic category: 3961
Product: D01799<JP>
Efficacy
Antidiabetic, Hypoglycemic, Sulfonylurea receptor agonist
Comment
Sulfonylurea
Target
ABCC8 (SUR1) [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus
Interaction
Structure map
map07018  Sulfonamide derivatives - hypoglycemic agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3961  Sulfonylureas
     D01799  Glyclopyramide (JAN/INN)
Drug groups [BR:br08330]
 Antidiabetic agent
  DG01508  Sulfonylurea receptor agonist
   DG01734  Sulfonylurea
    D01799  Glyclopyramide
  DG02044  Hypoglycemic agent
   DG01734  Sulfonylurea
    D01799  Glyclopyramide
Drug classes [BR:br08332]
 Antidiabetic agent
  DG01734  Sulfonylurea
   D01799  Glyclopyramide
  DG02044  Hypoglycemic agent
   D01799  Glyclopyramide
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8 (SUR1)
     D01799  Glyclopyramide (JAN/INN) <JP>
Other DBs
CAS: 631-27-6
PubChem: 7848861
ChEBI: 31658
LigandBox: D01799
NIKKAJI: J3.312J
LinkDB
KCF data

ATOM        19
            1   C8x C    10.8910  -17.8271
            2   C8y C    10.8910  -19.2312
            3   C8x C    12.0845  -19.9333
            4   C8x C    13.2780  -19.2312
            5   C8y C    13.2780  -17.8271
            6   C8x C    12.0845  -17.1251
            7   X   Cl    9.6273  -19.9333
            8   S4a S    14.4996  -17.1282
            9   N1b N    15.7114  -17.8342
            10  O3c O    15.4896  -16.1383
            11  O3c O    13.5097  -16.1383
            12  C5a C    16.8961  -17.1564
            13  N1b N    18.0835  -17.8482
            14  O5a O    16.9017  -15.7504
            15  N1y N    19.2801  -17.1635
            16  C1x C    20.5834  -17.5766
            17  C1x C    21.3820  -16.4671
            18  C1x C    20.5735  -15.3648
            19  C1x C    19.2753  -15.7930
BOND        20
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     6   1 1
            7     2   7 1
            8     5   8 1
            9     8   9 1
            10    8  10 2
            11    8  11 2
            12    9  12 1
            13   12  13 1
            14   12  14 2
            15   13  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   15  19 1

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