| Entry |
|
|---|
| Name |
Docarpamine (JAN/INN);
Tanadopa (TN) |
|---|
| Formula |
C21H30N2O8S
|
|---|
| Exact mass |
470.1723
|
|---|
| Mol weight |
470.5365
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
|
|---|
| Remark |
| Therapeutic category: | 2119 |
|
|---|
| Efficacy |
Cardiotonic, Dopamine D1 receptor agonist, beta1-Adrenergic receptor agonist |
|---|
| Comment |
Active form of prodrug: Dopamine [DR: D07870]
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
211 Cardiotonics
2119 Others
D01903 Docarpamine (JAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
D01903 Docarpamine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB1
D01903 Docarpamine (JAN/INN) <JP>
Dopamine
DRD1
D01903 Docarpamine (JAN/INN) <JP>
Prodrugs [br08324.html]
D01903
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 32
1 C8y C 14.9800 -16.5200
2 C8y C 14.9800 -15.1200
3 C8x C 16.2400 -14.4200
4 C8y C 17.4300 -15.1200
5 C8x C 17.4300 -16.5200
6 C8x C 16.2400 -17.2200
7 C1b C 18.6200 -14.4200
8 C1b C 19.8800 -15.1200
9 N1b N 21.0700 -14.4200
10 C5a C 22.2600 -15.1200
11 C1c C 23.5200 -14.4200
12 C1b C 24.7100 -15.1200
13 C1b C 25.9000 -14.4200
14 S2a S 27.1600 -15.1200
15 C1a C 28.3500 -14.4900
16 O7a O 13.7900 -14.4200
17 C7a C 12.6000 -15.1200
18 O7a O 11.4100 -14.4200
19 C1b C 10.1500 -15.1200
20 C1a C 8.9600 -14.4200
21 O7a O 13.7900 -17.2200
22 C7a C 13.7900 -18.6200
23 O7a O 12.6000 -19.3200
24 C1b C 12.6000 -20.7200
25 C1a C 11.4100 -21.4200
26 O6a O 12.6000 -16.5200
27 O6a O 14.9800 -19.3200
28 O5a O 22.2600 -16.5200
29 N1b N 23.5200 -13.0200
30 C5a C 24.7100 -12.3200
31 O5a O 24.7100 -10.9200
32 C1a C 25.9000 -13.0200
BOND 32
1 2 16 1
2 7 8 1
3 16 17 1
4 2 3 1
5 17 18 1
6 8 9 1
7 18 19 1
8 3 4 2
9 19 20 1
10 9 10 1
11 1 21 1
12 4 5 1
13 21 22 1
14 10 11 1
15 22 23 1
16 5 6 2
17 23 24 1
18 11 12 1
19 24 25 1
20 6 1 1
21 17 26 2
22 12 13 1
23 22 27 2
24 10 28 2
25 13 14 1
26 11 29 1 #Up
27 4 7 1
28 29 30 1
29 14 15 1
30 30 31 2
31 1 2 2
32 30 32 1
|
|---|
