| Entry |
|
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| Name |
Dextroamphetamine sulfate (USP);
Dexedrine (TN);
Dextrostat (TN) |
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| Product |
|
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| Generic |
DEXTROAMPHETAMINE (Bryant Ranch Prepack), DEXTROAMPHETAMINE (Tris Pharma), DEXTROAMPHETAMINE SULFATE (Actavis Pharma), DEXTROAMPHETAMINE SULFATE (Amneal Pharmaceuticals of New York LLC), DEXTROAMPHETAMINE SULFATE (Aurolife Pharma), DEXTROAMPHETAMINE SULFATE (Bryant Ranch Prepack), DEXTROAMPHETAMINE SULFATE (Bryant Ranch Prepack), DEXTROAMPHETAMINE SULFATE (Bryant Ranch Prepack), DEXTROAMPHETAMINE SULFATE (Bryant Ranch Prepack), DEXTROAMPHETAMINE SULFATE (KVK-Tech), DEXTROAMPHETAMINE SULFATE (Lupin Pharmaceuticals), DEXTROAMPHETAMINE SULFATE (Prasco Laboratories), DEXTROAMPHETAMINE SULFATE (SUNRISE PHARMACEUTICAL), DEXTROAMPHETAMINE SULFATE (SpecGx LLC), DEXTROAMPHETAMINE SULFATE (SpecGx LLC), DEXTROAMPHETAMINE SULFATE (Teva Pharmaceuticals USA), DEXTROAMPHETAMINE SULFATE (Tris Pharma), DEXTROAMPHETAMINE SULFATE (Wilshire Pharmaceuticals), DEXTROAMPHETAMINE SULFATE (Winder Laboratories LLC), PROCENTRA (INDEPENDENCE PHARMACEUTICALS), ZENZEDI (AZURITY PHARMACEUTICALS) |
|---|
| Formula |
(C9H13N)2. H2SO4
|
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| Exact mass |
368.177
|
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| Mol weight |
368.4909
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
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| Remark |
| Product (DG00967): | D03740<US> D02078<US> |
| Product (mixture): | D11624<US> |
|
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| Efficacy |
Stimulant (central) |
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| Disease |
Narcolepsy [DS: H01293] Attention deficit disorder with hyperactivity [DS: H01895] |
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| Target |
|
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| Pathway |
|
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| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
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| Interaction |
|
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| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06BA Centrally acting sympathomimetics
N06BA02 Dexamfetamine
D02078 Dextroamphetamine sulfate (USP) <US>
USP drug classification [BR:br08302]
Central Nervous System Agents
Attention Deficit Hyperactivity Disorder Agents, Amphetamines
Dextroamphetamine
D02078 Dextroamphetamine sulfate (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG00967 Dexamfetamine
D02078 Dextroamphetamine sulfate
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00967 Dexamfetamine
D02078 Dextroamphetamine sulfate
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D02078 Dextroamphetamine sulfate (USP) <US>
SLC6A3 (DAT1)
D02078 Dextroamphetamine sulfate (USP) <US>
SLC18
SLC18A2 (VMAT2)
D02078 Dextroamphetamine sulfate (USP) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D02078
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG00967 Dexamfetamine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00967 Dexamfetamine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C8y C 15.1900 -15.3300
2 C8x C 14.0000 -14.6300
3 C8x C 15.1900 -16.7300
4 C1b C 16.3800 -14.6300
5 C8x C 12.7400 -15.3300
6 C8x C 14.0000 -17.4300
7 C1c C 17.6400 -15.3300
8 C8x C 12.7400 -16.7300
9 N1a N 18.8300 -14.6300
10 C1a C 17.6400 -16.7300
11 S4a S 24.0800 -15.8900
12 O1d O 24.0800 -14.4900
13 O1d O 24.0800 -17.2900
14 O1d O 25.4800 -15.8900
15 O1d O 22.6800 -15.8900
16 C8y C 15.1900 -15.3300
17 C8x C 14.0000 -14.6300
18 C8x C 12.7400 -15.3300
19 C8x C 12.7400 -16.7300
20 C8x C 14.0000 -17.4300
21 C8x C 15.1900 -16.7300
22 C1b C 16.3800 -14.6300
23 C1c C 17.6400 -15.3300
24 N1a N 18.8300 -14.6300
25 C1a C 17.6400 -16.7300
BOND 24
1 11 12 2
2 11 13 2
3 11 14 1
4 11 15 1
5 1 2 2
6 1 3 1
7 1 4 1
8 2 5 1
9 3 6 2
10 4 7 1
11 5 8 2
12 7 9 1
13 7 10 1 #Up
14 6 8 1
15 16 17 2
16 16 21 1
17 16 22 1
18 17 18 1
19 21 20 2
20 22 23 1
21 18 19 2
22 23 24 1
23 23 25 1 #Up
24 20 19 1
BRACKET 1 12.1100 -18.4100 12.1100 -13.5100
1 20.3000 -13.5100 20.3000 -18.4100
1 2
ORIGINAL 1 1 2 5 8 6 3 4 7 9 10
REPEAT 1 16 17 18 19 20 21 22 23 24 25
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