KEGG   DRUG: Phendimetrazine tartrate
Entry
D02080                      Drug                                   
Name
Phendimetrazine tartrate (USP);
Bontril (TN);
Statobex (TN)
Product
  Generic
Formula
C12H17NO. C4H6O6
Exact mass
341.1475
Mol weight
341.3563
Structure
Class
Neuropsychiatric agent
 DG03085  Selective norepinephrine reuptake inhibitor (NRI)
Gastrointestinal agent
 DG01705  Anoretic
  DG01704  Phenethylamine anorexic
Remark
Chemical structure group: DG01537
Product (DG01537): D02080<US>
Efficacy
Appetite suppressant (systemic), Stimulant (central)
Comment
Morpholine derivative
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
  Pathway
hsa04721  Synaptic vesicle cycle
Interaction
Brite
USP drug classification [BR:br08302]
 Anti-Obesity Agents
  Phendimetrazine
   D02080  Phendimetrazine tartrate (USP)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03085  Selective norepinephrine reuptake inhibitor (NRI)
   DG01537  Phendimetrazine
    D02080  Phendimetrazine tartrate
 Gastrointestinal agent
  DG01705  Anoretic
   DG01704  Phenethylamine anorexic
    DG01537  Phendimetrazine
     D02080  Phendimetrazine tartrate
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D02080  Phendimetrazine tartrate (USP) <US>
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03085  Selective norepinephrine reuptake inhibitor (NRI)
   DG01537  Phendimetrazine
 Gastrointestinal agent
  DG01705  Anoretic
   DG01704  Phenethylamine anorexic
    DG01537  Phendimetrazine
Other DBs
CAS: 50-58-8
PubChem: 7849142
LigandBox: D02080
NIKKAJI: J244.783E
LinkDB
KCF data

ATOM        24
            1   C1y C    13.6729  -15.7602
            2   C8y C    12.3038  -16.4312
            3   C1y C    14.7975  -16.4891
            4   O2x O    13.6372  -14.3604
            5   C8x C    12.3396  -17.8310
            6   C8x C    11.1791  -15.7024
            7   N1y N    16.0266  -15.8181
            8   C1a C    14.7633  -17.8889
            9   C1x C    14.8663  -13.6894
            10  C8x C    11.1105  -18.5020
            11  C8x C     9.9502  -16.3733
            12  C1x C    16.0609  -14.4182
            13  C1a C    17.2214  -16.5470
            14  C8x C     9.9158  -17.7731
            15  O6a O    20.2528  -16.4966
            16  C6a C    21.4658  -15.7968
            17  C1c C    22.6788  -16.4966
            18  C1c C    23.8917  -15.7968
            19  C6a C    25.1047  -16.4966
            20  O6a O    21.4658  -14.3972
            21  O6a O    26.3176  -15.7968
            22  O6a O    25.1047  -17.8961
            23  O1a O    22.6788  -17.8961
            24  O1a O    23.8917  -14.3972
BOND        24
            1     1   2 1 #Down
            2     1   3 1
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     3   8 1 #Up
            8     4   9 1
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    7  13 1
            13   10  14 2
            14    9  12 1
            15   11  14 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   16  20 2
            21   19  21 1
            22   19  22 2
            23   17  23 1 #Up
            24   18  24 1 #Up

» Japanese version   » Back

DBGET integrated database retrieval system